Gut microbial flora, prebiotics, and probiotics in IBD: their current usage and utility.
Gut microbial flora, prebiotics, and probiotics in IBD: their current usage and utility.
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DOI：
10.1155/2013/435268
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发表时间：
2013
影响因子：
--
通讯作者：
Gasbarrini A
中科院分区：
文献类型：
--
作者：
Scaldaferri F;Gerardi V;Lopetuso LR;Del Zompo F;Mangiola F;Boškoski I;Bruno G;Petito V;Laterza L;Cammarota G;Gaetani E;Sgambato A;Gasbarrini A
炎症性肠病是影响胃肠道的慢性疾病，其主要形式以克罗恩病（CD）和溃疡性结肠炎（UC）为代表。其病因尚不清楚，虽然几个因素已被确定为诱导或复发的主要决定因素。其中，“被遗忘的器官”肠道微生物群的作用近年来越来越受到重视。肠道微生物群和宿主之间微妙的共生关系似乎在IBD中消失了。从这个角度来看，已经进行了几项研究来评估益生元和益生菌在肠道微生物群调节中的作用。这是一个小审查，旨在解决在一个简单的格式（简单的问题，简单的答案）有关的主题的一些常见问题。介绍了肠道微生物群选定成分在IBD发病机制中的作用的最新情况，并分析了益生元和益生菌管理IBD时肠道微生物群调节的功效。
Inflammatory bowel diseases are chronic diseases affecting the gastrointestinal tract, whose major forms are represented by Crohn's disease (CD) and ulcerative colitis (UC). Their etiology is still unclear, although several factors have been identified as major determinants for induction or relapses. Among these, the role of the “forgotten organ”, gut microbiota, has become more appreciated in recent years. The delicate symbiotic relationship between the gut microbiota and the host appears to be lost in IBD. In this perspective, several studies have been conducted to assess the role of prebiotics and probiotics in gut microbiota modulation. This is a minireview aimed to address in an easy format (simple questions-simple answers) some common issues about the theme. An update on the role of selected constituents of gut microbiota in the pathogenesis of IBD is presented together with the analysis of the efficacy of gut microbiota modulation by prebiotics and probiotics administration in the management of IBD.
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影响因子：
4.2
作者：
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通讯作者：
Lecannu, G
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