Learning to see: patterned visual activity and the development of visual function.
Learning to see: patterned visual activity and the development of visual function.
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DOI:
10.1016/j.tins.2010.01.003
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发表时间:
2010-04
影响因子:
15.9
通讯作者:
Aizenman, Carlos D.
中科院分区:
文献类型:
--
作者:
Ruthazer, Edward S.;Aizenman, Carlos D.
To successfully interact with their environment, developing organisms need to correctly process sensory information and generate motor output appropriate to their size and structure. Patterned sensory experience has long been known to induce various forms of developmental plasticity which ultimately shape mature neural circuits. Yet these same types of plasticity also allow developing organisms to respond appropriately to the external world by dynamically adapting neural circuit function to ongoing changes in brain circuitry and sensory input. Recent work on the visual system of frogs and fish has provided an unprecedented view into how visual experience dynamically affects circuit function at many levels, ranging from gene expression to network function, ultimately leading to system-wide functional adaptations.
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