Chitosan/nano-hydroxyapatite composite electret membranes enhance cell proliferation and osteoblastic expression in vitro
Chitosan/nano-hydroxyapatite composite electret membranes enhance cell proliferation and osteoblastic expression in vitro
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壳聚糖/纳米羟基磷灰石复合驻极体膜增强体外细胞增殖和成骨细胞表达
DOI：
10.1177/0883911513513094
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发表时间：
2014-01
影响因子：
1.7
通讯作者：
Man, Yi
中科院分区：
文献类型：
--
作者：
Qu, Yili;Ao, Danting;Wang, Ping;Wang, Yanying;Kong, Xiangli;Man, Yi
采用网格控制恒压电晕充电法制备了带负电荷的壳聚糖/纳米羟基磷灰石膜，并对其细胞生物相容性和骨诱导性能进行了研究。壳聚糖/纳米羟基磷灰石复合驻极体膜对成骨细胞的粘附、增殖和分化能力均有显著提高。本研究不仅为壳聚糖/纳米羟基磷灰石复合膜的临床应用提供了依据，也为壳聚糖/纳米羟基磷灰石复合膜的制备提供了策略依据。
Chitosan/nano-hydroxyapatite membranes with negative charges were fabricated by grid-controlled constant voltage corona charging, and the charged membranes were investigated for cell biocompatibility and osteoinduction. The osteoblasts on the chitosan/nano-hydroxyapatite composite electret membranes significantly enhanced the adhesion, proliferation, and differentiation capacity compared to the uncharged group. This study not only provides evidence for the potential clinical application of our novel membranes but also could be used as a strategy for chitosan/nano-hydroxyapatite scaffolds.
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DOI：
10.3791/1237
发表时间：
2009-07
期刊：
Journal of visualized experiments : JoVE
影响因子：
--
作者：
Brad M Isaacson;J. Stinstra;R. Macleod;J. Webster;J. P. Beck;R. Bloebaum
通讯作者：
Brad M Isaacson;J. Stinstra;R. Macleod;J. Webster;J. P. Beck;R. Bloebaum
影响因子：
56.9
作者：
G. Vogel
通讯作者：
G. Vogel
影响因子：
1.7
作者：
Yanying Wang;Rui Shi;P. Gong;Jidong Li;Juan Li;Danting Ao;Ping Wang;Yang Yang-Yang;Y. Man;Y. Qu
通讯作者：
Yanying Wang;Rui Shi;P. Gong;Jidong Li;Juan Li;Danting Ao;Ping Wang;Yang Yang-Yang;Y. Man;Y. Qu
影响因子：
1.7
作者：
Qingxiang Wang;Jiancong Ni;F. Gao;Bin Zhang;Shunxing Li;K. Jiao
通讯作者：
Qingxiang Wang;Jiancong Ni;F. Gao;Bin Zhang;Shunxing Li;K. Jiao
影响因子：
56.9
作者：
BASSETT, CAL;BECKER, RO
通讯作者：
BECKER, RO