Temporal lobe epilepsy in children.

Temporal lobe epilepsy in children.
复制标题

DOI:
10.1155/2012/849540
复制
发表时间:
2012
期刊:
Epilepsy research and treatment
影响因子:
--
通讯作者:
Wirrell EC
Wirrell EC
中科院分区:
其他
文献类型:
--
作者:
Nickels KC;Wong-Kisiel LC;Moseley BD;Wirrell EC

文献摘要

参考文献

被引文献

相似文献

颞叶是癫痫的常见病灶。婴儿和儿童的颞叶癫痫在几个重要的临床和病理方面与成人的相对同质综合征不同。癫痫的症状因年龄而异,发作期的脑电模式可能不像成年人那样清晰。此外,在发育中的大脑中发生顽固性癫痫发作可能会影响远离颞区的神经认知功能。虽然许多儿童对药物治疗的反应良好,但那些有局灶性影像异常的儿童可能难以治愈,包括皮质发育不良、海马体硬化症或低级别肿瘤。对于这些医学上难以解决的病例,需要适当的检查和手术干预,以最大限度地提高长期发育结果。
The temporal lobe is a common focus for epilepsy. Temporal lobe epilepsy in infants and children differs from the relatively homogeneous syndrome seen in adults in several important clinical and pathological ways. Seizure semiology varies by age, and the ictal EEG pattern may be less clear cut than what is seen in adults. Additionally, the occurrence of intractable seizures in the developing brain may impact neurocognitive function remote from the temporal area. While many children will respond favorably to medical therapy, those with focal imaging abnormalities including cortical dysplasia, hippocampal sclerosis, or low-grade tumors are likely to be intractable. Expedient workup and surgical intervention in these medically intractable cases are needed to maximize long-term developmental outcome.
DOI: 10.2337/db09-1105
发表时间: 2010-05
期刊: Diabetes
影响因子: 7.7
作者:
Curtis JM;Grimsrud PA;Wright WS;Xu X;Foncea RE;Graham DW;Brestoff JR;Wiczer BM;Ilkayeva O;Cianflone K;Muoio DE;Arriaga EA;Bernlohr DA
通讯作者: Bernlohr DA
DOI: 10.2337/db06-1076
发表时间: 2007-01-01
期刊: DIABETES
影响因子: 7.7
作者:
Lumeng, Carey N.;DeYoung, Stephanie M.;Saltiel, Alan R.
通讯作者: Saltiel, Alan R.
DOI: 10.1038/ijo.2010.12
发表时间: 2010-06
影响因子: 4.9
作者:
Grove, K. L.;Fried, S. K.;Greenberg, A. S.;Xiao, X. Q.;Clegg, D. J.
通讯作者: Clegg, D. J.
DOI: 10.2337/diabetes.51.9.2734
发表时间: 2002-09-01
期刊: DIABETES
影响因子: 7.7
作者:
Nishizawa, H;Shimomura, H;Matsuzawa, Y
通讯作者: Matsuzawa, Y
DOI: 10.1900/rds.2010.7.15
发表时间: 2010-01-01
期刊: The review of diabetic studies : RDS
影响因子: --
作者:
Pitocco, Dario;Zaccardi, Francesco;Ghirlanda, Giovanni
通讯作者: Ghirlanda, Giovanni