Tunable Particle Focusing in a Straight Channel with Symmetric Semicircle Obstacle Arrays Using Electrophoresis-Modified Inertial Effects.
Tunable Particle Focusing in a Straight Channel with Symmetric Semicircle Obstacle Arrays Using Electrophoresis-Modified Inertial Effects.
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DOI：
10.3390/mi7110195
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发表时间：
2016-11-01
期刊：
影响因子：
3.4
通讯作者：
Li W
中科院分区：
文献类型：
--
作者：
Yuan D;Pan C;Zhang J;Yan S;Zhao Q;Alici G;Li W
在这项工作中，提出了一种新型微流体平台，利用电泳（EP）改进的惯性效应，在具有对称半圆形障碍物阵列的直通道中进行可调谐粒子聚焦。通过对带电微粒施加EP力，在具有对称半圆形障碍物阵列的直通道中实现微球和流体之间的相对速度间隙。相对速度和流体剪切会产生垂直于主流方向的剪切滑移升力（萨夫曼升力）。因此，可以使用电泳引起的萨夫曼力来改变聚焦图案。还研究了电场方向、流速、电场强度和颗粒尺寸的影响。这证明了使用电泳在具有对称半圆形障碍物阵列的直通道中调整粒子惯性聚焦模式的可能性。控制聚焦条纹的横向迁移可提高血细胞过滤和按尺寸分离细胞等应用的可控性。
In this work, a novel microfluidic platform for tunable particle focusing in a straight channel with symmetric semicircle obstacle arrays using electrophoresis (EP)-modified inertial effects was presented. By exerting an EP force on the charged microparticles, a relative velocity gap between microspheres and fluid in a straight channel with symmetric semicircle obstacle arrays was implemented. The relative velocity and fluid shear will induce shear-slip lift force (Saffman lift force) perpendicular to the mainstream direction. Therefore, the focusing pattern can be altered using the electrophoresis-induced Saffman force. The effects of electric field direction, flow rate, electric field magnitude, and particle size were also studied. This demonstrates the possibility of adjusting the particle inertial focusing pattern in a straight channel with with symmetric semicircle obstacle arrays using electrophoresis. Manipulation of the lateral migration of focusing streaks increases controllability in applications such as blood cell filtration and the separation of cells by size.
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影响因子：
6.1
作者：
Kuntaegowdanahalli, Sathyakumar S.;Bhagat, Ali Asgar S.;Papautsky, Ian
通讯作者：
Papautsky, Ian
影响因子：
56.9
作者：
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作者：
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影响因子：
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作者：
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通讯作者：
Asmolov, ES
DOI：
10.1073/pnas.0704958104
发表时间：
2007-11-27
影响因子：
11.1
作者：
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通讯作者：
Toner, Mehmet