Circadian rhythms in infectious diseases and symbiosis.

Circadian rhythms in infectious diseases and symbiosis.
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DOI:
10.1016/j.semcdb.2021.09.004
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发表时间:
2022-06
影响因子:
7.3
通讯作者:
Takahashi, Joseph S.
Takahashi, Joseph S.
中科院分区:
生物学2区
文献类型:
--
作者:
Rijo-Ferreira, Filipa;Takahashi, Joseph S.

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时机就是一切生命之树上的许多生物都进化出了计时机制,这些机制通过预测环境的变化来调节它们的许多细胞功能,以优化时间。所感知的特定环境变化取决于生物体。对于动物,植物和自由生活的微生物,环境线索包括光/暗周期,每日温度波动等。相比之下,对于一个从来没有自由生活过的微生物来说,它的节奏环境就是宿主的节奏生物学。在这里,我们描述了最近的研究宿主和微生物之间的相互作用,从共生以及感染的角度。除了描述微生物的生物学,我们还特别关注生物钟如何调节这些宿主-微生物相互作用。
Timing is everything. Many organisms across the tree of life have evolved timekeeping mechanisms that regulate numerous of their cellular functions to optimize timing by anticipating changes in the environment. The specific environmental changes that are sensed depends on the organism. For animals, plants, and free-living microbes, environmental cues include light/dark cycles, daily temperature fluctuations, among others. In contrast, for a microbe that is never free-living, its rhythmic environment is its host’s rhythmic biology. Here, we describe recent research on the interactions between hosts and microbes, from the perspective both of symbiosis as well as infections. In addition to describing the biology of the microbes, we focus specifically on how circadian clocks modulate these host-microbe interactions.
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