Verification of Trail Making Test in Elderly People with Behavioral and Psychological Symptoms of Dementia

Verification of Trail Making Test in Elderly People with Behavioral and Psychological Symptoms of Dementia
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对患有痴呆症行为和心理症状的老年人进行追踪测试的验证

DOI:
10.1007/s12126-021-09424-y
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发表时间:
2021
影响因子:
1.5
通讯作者:
Fukunaga Shinya
Fukunaga Shinya
中科院分区:
--
文献类型:
--
作者:
Toda Atsushi;Nagami Shinsuke;Katsumata Ayako;Fukunaga Shinya

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在阿尔茨海默病 (AD) 中,注意力和执行功能障碍在疾病早期就会出现。然而,人们对这些疾病与痴呆症行为和心理症状(BPSD)之间的关系知之甚少。本研究调查了 BPSD 与注意力和执行功能之间的关系。 25 名患有轻度认知障碍 (MCI) 和早期 AD 的患者被纳入其中。对痴呆症患者进行神经心理学测试、简易精神状态检查(MMSE)、雷文彩色渐进材料(RCPM)和追踪测试(TMT)。痴呆行为障碍量表(DBD)用于痴呆患者的心理和行为评估。 AD组的MMSE、DBD和TMT-B评分显着低于MCI组。多元回归分析显示 DBD 评分、MMSE 和 TMT-B 之间存在显着相关性。结论:BPSD 与 MCI 和早期 AD 患者的认知功能严重程度相关,表明注意力和执行功能是这些神经基质的独立危险因素。
In Alzheimer's disease (AD), attention and executive dysfunction occur early in the disease. However, little is known about the relationship between these disorders and behavioral and psychological symptoms of dementia (BPSD). This study investigated the relationship between BPSD and attention and execution functions. Twenty-five patients with mild cognitive impairment (MCI) and early AD were included. Neuropsychological tests, mini-mental state examination (MMSE), Raven’s colored progressive materials (RCPM), and trail making test (TMT) were conducted for patients with dementia. The dementia behavior disturbance scale (DBD) was used for psychological and behavioral evaluations of patients with dementia. The AD group showed significantly lower MMSE, DBD, and TMT-B scores than the MCI group. Multiple regression analyses revealed a significant correlation between DBD score, MMSE, and TMT-B.Conclusion: BPSD is associated with cognitive function severity in patients with MCI and early AD, suggesting that attentional and executive functions are independent risk factors for these neural substrates.
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发表时间: 2016-11
期刊: The British journal of psychiatry : the journal of mental science
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