Clinical care is evolving: The microbiome for advanced practice nurses.
Clinical care is evolving: The microbiome for advanced practice nurses.
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临床护理正在不断发展：高级执业护士的微生物组。
DOI：
10.1097/jxx.0000000000000379
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发表时间：
2020
影响因子：
1.2
通讯作者：
Green,StefanJ
中科院分区：
文献类型：
--
作者：
Lockwood,MarkB;Green,StefanJ
在40亿年的时间里，人类与居住在我们体内的37万亿多微生物建立了亲密的关系。这种关系从共生关系到致病关系都有。微生物细胞的数量与体内哺乳动物细胞的数量大致相当。然而，由于宿主相关群落中大量的微生物多样性，微生物组的遗传含量大约是人类基因组的150倍。微生物基因编码的蛋白质能够产生对我们的健康和生存至关重要的各种分子。许多因素，如出生方式、饮食、氯化水和药物显著影响微生物组的丰富度和多样性。随着我们对微生物组对健康的影响的理解变得更好，高级执业护士作为临床医生、科学家、教育工作者和患者倡导者发挥着重要作用。了解微生物组如何影响个人健康或治疗效果将很快在临床环境中变得至关重要，应该鼓励护士自我教育我们的微生物伙伴，环境和人类健康之间的关系。
Over the course of four billion years, humans have developed an intimate relationship with the more than 37 trillion microbes that inhabit our bodies. This relationship runs the gamut from symbiosis to pathogenesis. The number of microbial cells is roughly equivalent to that of mammalian cells in the body. However, due to substantial microbial diversity in host-associated communities, the genetic content of the microbiome is roughly 150 times greater than that of the human genome. Microbial genes encode for proteins capable of producing a wide variety of molecules essential for our health and survival. Many factors such as mode of birth, diet, chlorination of water, and medications significantly affect the richness and diversity of the microbiome. Advanced practice nurses have important roles to play as clinicians, scientists, educators, and patient advocates as our understanding of the microbiome's effects on health becomes better articulated. An understanding of how the microbiome can affect an individual's health or the efficacy of treatment will soon be essential in the clinical setting, and nurses should be encouraged to educate themselves on the relationship between our microbial partners, the environment, and human health.
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DOI：
10.1126/science.1241214
发表时间：
2013-09-06
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Ridaura VK;Faith JJ;Rey FE;Cheng J;Duncan AE;Kau AL;Griffin NW;Lombard V;Henrissat B;Bain JR;Muehlbauer MJ;Ilkayeva O;Semenkovich CF;Funai K;Hayashi DK;Lyle BJ;Martini MC;Ursell LK;Clemente JC;Van Treuren W;Walters WA;Knight R;Newgard CB;Heath AC;Gordon JI
通讯作者：
Gordon JI
热纤梭菌纤维素酶对结晶纤维素降解的协同效应分析
DOI：
--
发表时间：
2019
期刊：
影响因子：
--
作者：
齋藤 翼;篠田 優;平野 勝紹;春木 満;平野 展孝
通讯作者：
平野 展孝
影响因子：
2.1
作者：
Neu J;Rushing J
通讯作者：
Rushing J
影响因子：
64.8
作者：
通讯作者：
--
影响因子：
6.1
作者：
Ursell LK;Metcalf JL;Parfrey LW;Knight R
通讯作者：
Knight R