Change in Asthma Is Associated with Change in PTSD in World Trade Center Health Registrants, 2011 to 2016.
Change in Asthma Is Associated with Change in PTSD in World Trade Center Health Registrants, 2011 to 2016.
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DOI：
10.3390/ijerph19137795
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发表时间：
2022-06-25
影响因子：
--
通讯作者：
Cone, James
中科院分区：
文献类型：
--
作者：
Friedman, Stephen M.;Alper, Howard;de la Hoz, Rafael E.;Osahan, Sukhminder;Farfel, Mark R.;Cone, James
世贸中心健康登记处是一个封闭的纵向队列，记录了2001年9月11日灾难中的救援/恢复工作人员和幸存者。2001年9月11日之后诊断为哮喘的WTCLN登记者尽管接受了治疗，但仍控制不佳。哮喘与精神问题有关，尽管它们的双向运动尚未被研究。本研究测试了精神问题的临床变化是否与哮喘控制的差异相关，以及哮喘控制的变化是否随生活质量（QoL）的变化而变化。将2011-12年至2015-16年WTweek哮喘控制测试（ACT）的差异与创伤后应激障碍量表（PCL-17），患者健康问卷抑郁量表，自我报告的胃灼热以及这一时期身心QoL的变化进行比较。在校正的多项多变量logistic回归中，PCL-17改善与ACT评分改善相关，比值比（OR）= 1.42（95% CI）。PCL-17评分恶化与ACT评分恶化相关，OR = 1.77（95% C.I. 1.26，2.50）。ACT降低与身体生活质量差相关，OR = 1.97（95% C.I. 1.48，2.62）。心理健康指标的变化与哮喘控制的变化相关联，这与生活质量的变化相关。仔细的后续行动和治疗的所有三个，以改善这些相互关联的问题。
The WTC Health Registry (WTCHR) is a closed, longitudinal cohort of rescue/recovery workers and survivors exposed to the 11 September 2001 disaster. WTCHR enrollees diagnosed with asthma after 11 September 2001 continued to experience poor control despite treatment. Asthma is associated with mental problems, although their bidirectional movement has not been studied. This study tested whether a clinical change in mental problems was associated with a difference in asthma control, and whether a change in asthma control varied with a change in quality of life (QoL). Difference in the Asthma Control Test (ACT) on the WTCHR from 2011–12 to 2015–16 was compared with the change in the Post-traumatic Stress Disorder Checklist (PCL-17), the Patient Health Questionnaire depression scale, self-reported heartburn, and change of physical and mental QoL over this period. In adjusted multinomial multivariable logistic regression, improved PCL-17 was associated with a better ACT score, odds ratio (OR) = 1.42 (95% C.I. 1.01, 1.99), and a worsened PCL-17 score was associated with a worsened ACT score, OR = 1.77 (95% C.I. 1.26, 2.50). Decreased ACT was associated with poor physical QoL, OR = 1.97 (95% C.I. 1.48, 2.62). Change in mental health measures tracked with change in asthma control, which correlated with a change in QoL. Careful follow-up and treatment of all three are indicated to improve these inter-related issues.
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影响因子：
14.2
作者：
Rosenberg, Stacy L.;Miller, Gregory E.;Celedon, Juan C.
通讯作者：
Celedon, Juan C.
DOI：
10.1164/rccm.201605-1067oc
发表时间：
2016-12-01
影响因子：
24.7
作者：
de la Hoz, Rafael E.;Jeon, Yunho;Celedon, Juan C.
通讯作者：
Celedon, Juan C.
影响因子：
24.3
作者：
Spitzer, C.;Koch, B.;Schaeper, C.
通讯作者：
Schaeper, C.
影响因子：
24.3
作者：
Bateman, E. D.;Bousquet, J.;Pedersen, S. E.
通讯作者：
Pedersen, S. E.
DOI：
10.1007/s11524-008-9317-4
发表时间：
2008-11-01
影响因子：
6.6
作者：
Farfel, Mark;DiGrande, Laura;Thorpe, Lorna
通讯作者：
Thorpe, Lorna