Variation in the fruit development gene POINTED TIP regulates protuberance of tomato fruit tip.
Variation in the fruit development gene POINTED TIP regulates protuberance of tomato fruit tip.
复制标题
果实发育基因 POINTED TIP 的变异调节番茄果尖的突起
DOI:
10.1038/s41467-022-33648-4
复制
发表时间:
2022-10-08
影响因子:
16.6
通讯作者:
中科院分区:
文献类型:
--
作者:
The domestication of tomato has led to striking variations in fruit morphology. Here, we show a genome-wide association study (GWAS) to understand the development of the fruit tip and describe aPOINTED TIP(PT) gene that encodes a C2H2-type zinc finger transcription factor. A single nucleotide polymorphism is found to change a histidine (H) to an arginine (R) in the C2H2 domain of PT and the two alleles are referred to asPTHandPTR. Knocking outPTHleads to development of pointed tip fruit.PTHfunctions to suppress pointed tip formation by downregulating the transcription ofFRUTFULL 2(FUL2), which alters the auxin transport. Our evolutionary analysis and previous studies by others suggest that thePTRallele likely hitch-hiked along with other selected loci during the domestication process. This study uncovers variation inPTand molecular mechanism underlying fruit tip development in tomato.
登录
查看更多内容
影响因子:
4.4
作者:
Colasanti J;Tremblay R;Wong AY;Coneva V;Kozaki A;Mable BK
通讯作者:
Mable BK
影响因子:
8.7
作者:
Lu J;Pan C;Li X;Huang Z;Shu J;Wang X;Lu X;Pan F;Hu J;Zhang H;Su W;Zhang M;Du Y;Liu L;Guo Y;Li J
通讯作者:
Li J
影响因子:
30.8
作者:
Cong, Bin;Barrero, Luz S.;Tanksley, Steven D.
通讯作者:
Tanksley, Steven D.
影响因子:
3.5
作者:
Pandolfini T;Rotino GL;Camerini S;Defez R;Spena A
通讯作者:
Spena A
影响因子:
3
作者:
Barrios-Masias, Felipe H.;Chetelat, Roger T.;Jackson, Louise E.
通讯作者:
Jackson, Louise E.