Reproducibility and Reliability of Spectralis II OCT Angiography Vascular Measurements.
Reproducibility and Reliability of Spectralis II OCT Angiography Vascular Measurements.
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DOI：
10.3390/diagnostics12081908
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发表时间：
2022-08-07
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影响因子：
--
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中科院分区：
文献类型：
--
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目的：研究使用Heidelberg Spectralis II OCT-A进行OCT-A血管测量的重现性和可靠性。方法：一项前瞻性研究，涉及18岁或以上无眼部疾病的单眼患者。为探讨第一次和第二次OCT A扫描的可靠性，计算了黄斑中心凹无血管区（FAZ）的变异系数和浅（SCP）、中（ICP）和深毛细血管丛（DCP）的血管密度（VD）。结果：共75只眼纳入研究。SCP第一次和第二次扫描的平均FAZ分别为0.36 × 0.13 mm 2和0.37 × 0.12 mm 2，ICP为0.23 × 0.10 mm 2和0.23 × 0.09 mm 2，DCP为0.42 × 0.11 mm 2和0.43 × 0.12 mm 2。SCP第一次和第二次扫描的总VD分别为36.05 × 9.01和35.33 × 9.92，ICP为21.87 × 5.00和21.32 × 5.56，DCP为23.84 × 6.53和23.20 × 6.83。第一次和第二次扫描之间每个毛细血管丛所有区段的FAZ测量值和VD无统计学显著差异（p > 0.05）。结论：我们的研究证明了OCT-A血管测量在分析FAZ和定量视网膜的每个毛细血管丛中的VD中的良好再现性和可靠性。
Purpose: to investigate the reproducibility and reliability of OCT-A vascular measurements using Heidelberg Spectralis II OCT-A. Methods: a prospective study involving a single eye of patients aged 18 or older with no ocular disease. In order to investigate the reliability of the first and second OCT-A scans, the coefficient of variation of the foveal avascular zone (FAZ) and the vessel density (VD) in the superficial (SCP), intermediate (ICP) and deep capillary plexus (DCP) were calculated. Results: A total of 75 eyes were included in the study. The mean FAZ in the first and second scan was 0.36 × 0.13 mm2 and 0.37 × 0.12 mm2, respectively, in the SCP, 0.23 × 0.10 mm2 and 0.23 × 0.09 mm2 in the ICP, and 0.42 × 0.11 mm2 and 0.43 × 0.12 mm2 in the DCP. The overall VD was 36.05 × 9.01 and 35.33 × 9.92 at the first and second scan, respectively, in the SCP, 21.87 × 5.00 and 21.32 × 5.56 in the ICP, and 23.84 × 6.53 and 23.20 × 6.83 in the DCP. No statistically significant differences in FAZ measurements and VD in all sectors of each capillary plexus were observed between the first and second scan (p > 0.05). Conclusion: our study demonstrated the good reproducibility and reliability of OCT-A vascular measurements in the analysis of the FAZ and the quantification of VD in each capillary plexus of the retina.
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影响因子：
13.7
作者：
Jia Y;Wei E;Wang X;Zhang X;Morrison JC;Parikh M;Lombardi LH;Gattey DM;Armour RL;Edmunds B;Kraus MF;Fujimoto JG;Huang D
通讯作者：
Huang D
影响因子：
3.7
作者：
Munk MR;Giannakaki-Zimmermann H;Berger L;Huf W;Ebneter A;Wolf S;Zinkernagel MS
通讯作者：
Zinkernagel MS
影响因子：
3.7
作者：
Rabiolo A;Gelormini F;Sacconi R;Cicinelli MV;Triolo G;Bettin P;Nouri-Mahdavi K;Bandello F;Querques G
通讯作者：
Querques G
影响因子：
3.8
作者：
Jia Y;Tan O;Tokayer J;Potsaid B;Wang Y;Liu JJ;Kraus MF;Subhash H;Fujimoto JG;Hornegger J;Huang D
通讯作者：
Huang D
影响因子：
4.4
作者：
Tan, Priscilla Ern Zhi;Yu, Paula K.;Yu, Dao-Yi
通讯作者：
Yu, Dao-Yi