Adult outcomes of childhood dysregulation: a 14-year follow-up study.

Adult outcomes of childhood dysregulation: a 14-year follow-up study.
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DOI:
10.1016/j.jaac.2010.08.006
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发表时间:
2010-11
影响因子:
13.3
通讯作者:
van der Ende J
van der Ende J
中科院分区:
医学1区
文献类型:
--
作者:
Althoff RR;Verhulst FC;Rettew DC;Hudziak JJ;van der Ende J

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使用一般人群样本,我们的目的是检查在儿童行为检查表(cbcl -失调概况)中同时在注意力问题、攻击行为和焦虑抑郁方面被评为严重自我调节问题的儿童的成年结果。1983年,从荷兰出生登记处抽取了年龄在4至16岁之间的13个出生队列中的2076名儿童。当来自不同队列的儿童年龄在4-16岁时,父母在基线时完成儿童行为检查表(CBCLs),并在接下来的14年中每两年抽样一次。在第14年收集CBCL和DSM访谈数据。使用逻辑回归来比较和对比有和没有失调的儿童的结果,通过潜在类别定义的CBCL-DP来测量。性别和年龄共变,同时DSM诊断纳入回归模型。第1波儿童CBCL-DP的存在与14年后成人焦虑症、情绪障碍、破坏性行为障碍和药物滥用的发生率增加有关。在控制了成年期共同发生的障碍后,焦虑和破坏性行为障碍与CBCL-DP的关联仍然存在,而其他的则不显著。据报道,属于CBCL-DP类的儿童在成年后出现调节情感、行为和认知问题的风险增加。
Using a general population sample, we aimed to examine the adult outcomes of children who present with severe problems with self-regulation defined as being concurrently rated highly on attention problems, aggressive behavior, and anxious-depression on the Child Behavior Checklist (the CBCL-Dysregulation Profile). 2,076 children from 13 birth cohorts aged 4 to 16 were drawn from Dutch birth registries in 1983. Child Behavior Checklists (CBCLs) were completed by parents at baseline when children from the different cohorts were ages 4-16 and sampled every 2 years for the next 14-years. At year 14 both CBCL and DSM interview data were collected. Logistic regression was used to compare and contrast outcomes for children with and without dysregulation, as measured by the latent-class-defined CBCL-DP. Sex and age were covaried and concurrent DSM diagnoses were included in regression models. Presence of childhood CBCL-DP at Wave 1 was associated with increased rates of adult anxiety disorders, mood disorders, disruptive behavior disorders, and drug abuse 14 years later. After controlling for co-occurring disorders in adulthood, the associations with anxiety and disruptive behavior disorders with the CBCL-DP remained while the others were not significant. A child reported to be in the CBCL-DP class is at increased risk for problems with regulating affect, behavior, and cognition in adulthood.
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发表时间: 2006-11-01
影响因子: 10.6
作者:
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发表时间: 2006-11-01
影响因子: 10.6
作者:
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