An Overview of the Use of Equine Collagen as Emerging Material for Biomedical Applications.
An Overview of the Use of Equine Collagen as Emerging Material for Biomedical Applications.
复制标题
DOI：
10.3390/jfb11040079
复制
发表时间：
2020-11-01
影响因子：
4.8
通讯作者：
Salvatore L
中科院分区：
文献类型：
--
作者：
Gallo N;Natali ML;Sannino A;Salvatore L
I型胶原蛋白以其良好的结构特性和生物活性在生命科学和生物工程领域引起了人们极大的兴趣。因此，在过去的五十年中，它已被广泛研究并用作制造植入式医疗器械的生物材料。常用的胶原蛋白来源以牛和猪为代表，但由于人畜共患病传播风险、免疫反应和宗教限制，其应用受到限制。因此，从马肌腱分离的I型胶原蛋白作为一种有吸引力的替代品最近获得了越来越多的关注，因此，尽管牛和猪衍生的胶原蛋白仍然是最常见的胶原蛋白，但越来越多的公司开始将各种基于马胶原蛋白的产品推向市场。在这种情况下，这项工作的目的是概述马胶原蛋白的特性，使其在医学，化妆品和制药方面特别有吸引力，以及其主要的生物医学应用和目前批准的基于马胶原蛋白的医疗器械，重点是过去15年的实验研究和临床试验。据我们所知，这是第一次审查，重点是使用马胶原蛋白，以及对马胶原蛋白为基础的上市产品的医疗保健。
Type I collagen has always aroused great interest in the field of life-science and bioengineering, thanks to its favorable structural properties and bioactivity. For this reason, in the last five decades it has been widely studied and employed as biomaterial for the manufacture of implantable medical devices. Commonly used sources of collagen are represented by bovine and swine but their applications are limited because of the zoonosis transmission risks, the immune response and the religious constrains. Thus, type-I collagen isolated from horse tendon has recently gained increasing interest as an attractive alternative, so that, although bovine and porcine derived collagens still remain the most common ones, more and more companies started to bring to market a various range of equine collagen-based products. In this context, this work aims to overview the properties of equine collagen making it particularly appealing in medicine, cosmetics and pharmaceuticals, as well as its main biomedical applications and the currently approved equine collagen-based medical devices, focusing on experimental studies and clinical trials of the last 15 years. To the best of our knowledge, this is the first review focusing on the use of equine collagen, as well as on equine collagen-based marketed products for healthcare.
登录
查看更多内容
影响因子：
3.6
作者：
Banerjee, Indranil;Mishra, Debasish;Maiti, Tapas K.
通讯作者：
Maiti, Tapas K.
DOI：
10.1023/a:1007074314686
发表时间：
2000-02-01
期刊：
JOURNAL OF PROTEIN CHEMISTRY
影响因子：
--
作者：
Brown, EM;Farrell, HM;Wildermuth, RJ
通讯作者：
Wildermuth, RJ
DOI：
10.3390/ma10091086
发表时间：
2017-09-15
期刊：
Materials (Basel, Switzerland)
影响因子：
--
作者：
Böhm S;Strauß C;Stoiber S;Kasper C;Charwat V
通讯作者：
Charwat V
影响因子：
10.8
作者：
Badieyan, Zohreh Sadat;Berezhanskyy, Taras;Plank, Christian
通讯作者：
Plank, Christian
DOI：
10.1080/02844319850158732
发表时间：
1998-06-01
影响因子：
--
作者：
Bang, K;Sampram, E;Hjortdal, VE
通讯作者：
Hjortdal, VE