Intermittent Fasting and Sleep: A Review of Human Trials.
Intermittent Fasting and Sleep: A Review of Human Trials.
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DOI：
10.3390/nu13103489
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发表时间：
2021-10-01
期刊：
影响因子：
5.9
通讯作者：
Varady KA
中科院分区：
文献类型：
--
作者：
McStay M;Gabel K;Cienfuegos S;Ezpeleta M;Lin S;Varady KA
这篇综述研究了两种流行的间歇性禁食对超重和肥胖成年人睡眠的影响。具体而言，将总结限时进食（TRE，在4-10小时内进食所有食物）和隔日禁食（ADF， 600千卡禁食日与任意盛宴日交替）对睡眠质量、睡眠持续时间、睡眠潜伏期、睡眠效率、失眠严重程度和阻塞性睡眠呼吸暂停风险的影响。减肥的作用也将被讨论。我们回顾的结果显示，这些试验中的大多数产生的体重减轻幅度在基线的1-6%之间。通过匹兹堡睡眠质量指数（PSQI）评估，TRE和ADF的睡眠质量和睡眠时间保持不变。间歇性禁食对睡眠潜伏期和睡眠效率的影响好坏参半，一项研究显示这些参数恶化，而其他研究显示没有影响。在评估这些指标的试验中，失眠严重程度和阻塞性睡眠呼吸暂停的风险保持不变。综上所述，这些初步研究结果表明，TRE和ADF可以产生轻度至中度的体重减轻（1-6%），但它们对睡眠的影响尚不清楚。可靠的结论很难建立，因为研究的参与者有健康的睡眠时间，在基线时没有临床失眠，这些指标几乎没有改进的空间。此外，这些试验都没有足够的能力来检测任何睡眠指标的统计学显著变化。为了阐明这些流行饮食对睡眠的影响，未来有必要在诊断为睡眠障碍的个体中进行有力的试验。
This review examines the effects of two popular intermittent fasting regimens on sleep in adults with overweight and obesity. Specifically, the effects of time restricted eating (TRE; eating all food within a 4–10 h window) and alternate day fasting (ADF; 600 kcal fast day alternated with ad libitum feast day) on sleep quality, sleep duration, sleep latency, sleep efficiency, insomnia severity, and risk of obstructive sleep apnea, will be summarized. The role of weight loss will also be discussed. Results from our review reveal that the majority of these trials produced weight loss in the range of 1–6% from baseline. Sleep quality and sleep duration remained unaltered with TRE and ADF, as assessed by the Pittsburgh Sleep Quality Index (PSQI). The effects of intermittent fasting on sleep latency and sleep efficiency are mixed, with one study showing worsening of these parameters, and others showing no effect. Insomnia severity and the risk of obstructive sleep apnea remained unchanged in the trials assessing these metrics. Taken together, these preliminary findings suggest that TRE and ADF produce mild to moderate weight loss (1–6%) but their effects on sleep remain unclear. Solid conclusions are difficult to establish since participants in the studies had healthy sleep durations and no clinical insomnia at baseline, leaving little room for improvement in these metrics. Moreover, none of the trials were adequately powered to detect statistically significant changes in any measure of sleep. Future well-powered trials, conducted in individuals with diagnosed sleep disturbances, will be necessary to elucidate the effect of these popular diets on sleep.
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