In search of features that constitute an "enriched environment" in humans: Associations between geographical properties and brain structure.

In search of features that constitute an "enriched environment" in humans: Associations between geographical properties and brain structure.
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DOI:
10.1038/s41598-017-12046-7
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发表时间:
2017-09-20
期刊:
影响因子:
4.6
通讯作者:
Lindenberger U
Lindenberger U
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Kühn S;Düzel S;Eibich P;Krekel C;Wüstemann H;Kolbe J;Martensson J;Goebel J;Gallinat J;Wagner GG;Lindenberger U

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丰富的环境激发了动物的大脑可塑性。在人类身上,目前还不清楚哪种环境是富营养化的。生活在城市与应激范式中杏仁核活动增加有关,并且在前代扣带回皮质(PACC)活动增加的城市长大。我们着手确定构成影响人脑的丰富环境的地理特征。我们使用结构方程模型在341名老年人身上建立了三个潜在的脑因素(杏仁核、pACC和前额叶背外侧皮质(DLPFC)),以测试家庭住址周围的森林、城市绿地、水和荒地的影响。我们的结果显示,森林覆盖率和杏仁核完整性之间存在显著的正相关。我们得出结论,森林可能对杏仁核的完整性有有益健康的作用。由于横断面数据不允许因果推断,结构完整性高的个体也可能选择居住在离森林更近的地方。
Enriched environments elicit brain plasticity in animals. In humans it is unclear which environment is enriching. Living in a city has been associated with increased amygdala activity in a stress paradigm, and being brought up in a city with increased pregenual anterior cingulate cortex (pACC) activity. We set out to identify geographical characteristics that constitute an enriched environment affecting the human brain. We used structural equation modelling on 341 older adults to establish three latent brain factors (amygdala, pACC and dorsolateral prefrontal cortex (DLPFC)) to test the effects of forest, urban green, water and wasteland around the home address. Our results reveal a significant positive association between the coverage of forest and amygdala integrity. We conclude that forests may have salutogenic effects on the integrity of the amygdala. Since cross-sectional data does not allow causal inference it could also be that individuals with high structural integrity choose to live closer to forest.
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