Living with tics: reduced impairment and improved quality of life for youth with chronic tic disorders.
Living with tics: reduced impairment and improved quality of life for youth with chronic tic disorders.
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DOI：
10.1016/j.psychres.2014.11.045
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发表时间：
2015-02-28
影响因子：
11.3
通讯作者：
Storch, Eric A.
中科院分区：
文献类型：
--
作者：
McGuire, Joseph F.;Arnold, Elysse;Park, Jennifer M.;Nadeau, Joshua M.;Lewin, Adam B.;Murphy, Tanya K.;Storch, Eric A.
关键词：
药物和行为干预侧重于降低抽动的严重程度，以减轻患有慢性抽动障碍(CTDS)的青少年抽动相关的损害，目前还没有针对抽动的不良心理社会后果的干预措施。这项研究考察了模块化认知行为干预(“抽搐生活”，LWT)与同等持续时间的等待名单对照相比，在减少抽动相关的损害和改善生活质量方面的初步效果。24名患有多发性抽动障碍或慢性抽动障碍并有心理社会障碍的青少年(7-17岁)参加了研究。治疗盲人评估者进行治疗前和治疗后临床医生评定的所有措施。青年被随机分配接受LWT干预(n=12)或10周等待名单(n=12)。LWT干预包括每周最多10次会议，旨在减少抽动相关的损害，并发展管理抽动的心理社会后果的技能。处于LWT状态的年轻人显著减少了临床医生评估的抽动障碍，并提高了儿童评估的生活质量。在LWT组中，有10名青年(83%)被归类为治疗应答者，而在等待名单情况下，有4名青年(33%)。在一个月的随访中，治疗收益保持不变。研究结果提供了初步数据，即LWT干预减少了抽动相关的损害，并改善了患有CTDS的青少年的生活质量。
Pharmacological and behavioral interventions have focused on reducing tic severity to alleviate tic-related impairment for youth with chronic tic disorders (CTDs), with no existing intervention focused on the adverse psychosocial consequences of tics. This study examined the preliminary efficacy of a modularized cognitive behavioral intervention ("Living with Tics", LWT) in reducing tic-related impairment and improving quality of life relative to a waitlist control of equal duration. Twenty-four youth (ages 7–17 years) with Tourette Disorder or Chronic Motor Tic Disorder and psychosocial impairment participated. A treatment-blind evaluator conducted all pre- and post-treatment clinician-rated measures. Youth were randomly assigned to receive the LWT intervention (n=12) or a 10-week waitlist (n=12). The LWT intervention consisted of up to 10 weekly sessions targeted at reducing tic-related impairment and developing skills to manage psychosocial consequences of tics. Youth in the LWT condition experienced significantly reduced clinician-rated tic-impairment, and improved child-rated quality of life. Ten youth (83%) in the LWT group were classified as treatment responders compared to four youth in the waitlist condition (33%). Treatment gains were maintained at one-month follow-up. Findings provide preliminary data that the LWT intervention reduces tic-related impairment and improves quality of life for youth with CTDs.
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影响因子：
6.4
作者：
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通讯作者：
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DOI：
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发表时间：
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影响因子：
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作者：
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