Animal Rabies Surveillance, China, 2004-2018.

Animal Rabies Surveillance, China, 2004-2018.
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DOI:
10.3201/eid2612.200303
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发表时间:
2020-12
影响因子:
11.8
通讯作者:
Tu C
Tu C
中科院分区:
医学2区
文献类型:
--
作者:
Feng Y;Wang Y;Xu W;Tu Z;Liu T;Huo M;Liu Y;Gong W;Zeng Z;Wang W;Wei Y;Tu C

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狂犬病在中国是一种严重的人畜共患疾病,但狂犬病病毒(RABV)在动物宿主中的传播和分布尚不清楚。我们报告了中国首个狂犬病监测计划对动物种群进行15年监测的结果,其中对2004-2018年收集的动物脑组织进行了RABV检测,并使用获得的RABV序列进行了系统发育和时空进化分析。结果提供了迄今为止中国rabv感染动物种类、地理分布、传播来源和遗传多样性最全面的数据集。特别是,新出现的RABV亚分支在中国与邻国之间的跨界传播得到了证实。该研究强调了持续监测动物狂犬病在监测传播动态方面的重要性,并为在源头改进当前的控制和预防战略提供了最新信息。
Rabies is a severe zoonotic disease in China, but the circulation and distribution of rabies virus (RABV) within animal reservoirs is not well understood. We report the results of 15 years of surveillance of the first Chinese Rabies Surveillance Plan in animal populations, in which animal brain tissues collected during 2004–2018 were tested for RABV and phylogenetic and spatial–temporal evolutionary analyses performed using obtained RABV sequences. The results have provided the most comprehensive dataset to date on the infected animal species, geographic distribution, transmission sources, and genetic diversity of RABVs in China. In particular, the transboundary transmission of emerging RABV subclades between China and neighboring countries was confirmed. The study highlights the importance of continuous animal rabies surveillance in monitoring the transmission dynamics, and provides updated information for improving current control and prevention strategies at the source.
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