A qualitative meta-analysis reveals consistent effects of atrazine on freshwater fish and amphibians.
A qualitative meta-analysis reveals consistent effects of atrazine on freshwater fish and amphibians.
复制标题
DOI：
10.1289/ehp.0901164
复制
发表时间：
2010-01
影响因子：
10.4
通讯作者：
McCoy KA
中科院分区：
文献类型：
--
作者：
Rohr JR;McCoy KA
除草剂阿特拉津对淡水脊椎动物的生物学影响存在很大争议。为了解决这一争议，我们对生态相关的阿特拉津浓度对两栖动物和鱼类生存、行为、变态特征、感染以及免疫、内分泌和生殖系统的影响进行了定性荟萃分析。我们使用已发表的同行评审研究，并采用严格的质量标准纳入荟萃分析中的研究。我们几乎没有发现阿特拉津持续导致鱼类或两栖动物直接死亡的证据，但我们发现它可能具有间接和亚致死效应的证据。阿特拉津浓度与两栖类变态时间呈规律性的非单调关系，表明阿特拉津既能加速变态，又能延迟变态。阿特拉津在17项研究中的15项和14个物种中的14个在变态或接近变态时减小了尺寸。阿特拉津在13项研究中的12项中升高了两栖动物和鱼类的活动，在7项研究中的6项中降低了反捕食行为，并降低了鱼类的嗅觉能力，但对两栖动物没有影响。阿特拉津与43个免疫功能终点中的33个降低相关，与16个感染终点中的13个增加相关。阿特拉津在10项研究中的7项中改变了性腺形态的至少一个方面，并持续影响性腺功能，在2项研究中的2项中改变了精子发生，在7项研究中的6项中改变了性激素浓度。阿特拉津在5项研究中不影响卵黄蛋白原，仅在1/6项研究中增加芳香化酶。阿特拉津对鱼类和两栖类繁殖成功率、性别比例、基因频率、种群和群落的影响仍不确定。虽然关于阿特拉津的影响还有很多东西需要了解，但我们确定了阿特拉津的几个一致影响，必须与其任何好处以及阿特拉津替代品的成本和好处进行权衡。
The biological effects of the herbicide atrazine on freshwater vertebrates are highly controversial. In an effort to resolve the controversy, we conducted a qualitative meta-analysis on the effects of ecologically relevant atrazine concentrations on amphibian and fish survival, behavior, metamorphic traits, infections, and immune, endocrine, and reproductive systems. We used published, peer-reviewed research and applied strict quality criteria for inclusion of studies in the meta-analysis. We found little evidence that atrazine consistently caused direct mortality of fish or amphibians, but we found evidence that it can have indirect and sublethal effects. The relationship between atrazine concentration and timing of amphibian metamorphosis was regularly nonmonotonic, indicating that atrazine can both accelerate and delay metamorphosis. Atrazine reduced size at or near metamorphosis in 15 of 17 studies and 14 of 14 species. Atrazine elevated amphibian and fish activity in 12 of 13 studies, reduced antipredator behaviors in 6 of 7 studies, and reduced olfactory abilities for fish but not for amphibians. Atrazine was associated with a reduction in 33 of 43 immune function end points and with an increase in 13 of 16 infection end points. Atrazine altered at least one aspect of gonadal morphology in 7 of 10 studies and consistently affected gonadal function, altering spermatogenesis in 2 of 2 studies and sex hormone concentrations in 6 of 7 studies. Atrazine did not affect vitellogenin in 5 studies and increased aromatase in only 1 of 6 studies. Effects of atrazine on fish and amphibian reproductive success, sex ratios, gene frequencies, populations, and communities remain uncertain. Although there is much left to learn about the effects of atrazine, we identified several consistent effects of atrazine that must be weighed against any of its benefits and the costs and benefits of alternatives to atrazine use.
登录
查看更多内容
影响因子：
4.1
作者：
Diana, SG;Resetarits, WJ;Beasley, VR
通讯作者：
Beasley, VR
影响因子：
5
作者：
Gallant, AL;Hansen, AJ;Betz, DW
通讯作者：
Betz, DW
影响因子：
8.8
作者：
Du Preez, Louis H.;Kunene, Nisile;Van Der Kraak, Glen J.
通讯作者：
Van Der Kraak, Glen J.
影响因子：
4.1
作者：
Brodkin, Marc A.;Madhoun, Hareth;Vatnick, Itzick
通讯作者：
Vatnick, Itzick
DOI：
10.1080/15287390490443722
发表时间：
2004-06-25
影响因子：
2.6
作者：
Coady, KK;Murphy, MB;Giesy, JP
通讯作者：
Giesy, JP