Value-based modulations in human visual cortex.

Value-based modulations in human visual cortex.
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DOI:
10.1016/j.neuron.2008.10.051
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发表时间:
2008-12-26
期刊:
影响因子:
16.2
通讯作者:
Serences, John T.
Serences, John T.
中科院分区:
医学1区
文献类型:
--
作者:
Serences, John T.

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经济学家和认知心理学家早就知道,先前的奖励会使决策偏向于高预期价值的选择。因此,价值调节了感觉运动神经元的活动,这些神经元参与了向两个相互竞争的决策选择之一发起运动。然而,关于价值如何影响传入感官信息的获取和表征,或者关于跟踪每个可用刺激的相对价值以指导行为的神经机制,我们知之甚少。在这里,fMRI揭示了在没有明显的跳眼反应(包括V1)的情况下,整个人类视觉系统的空间选择性区域的价值相关调制。这些调节主要与每个刺激的奖励历史有关,而不是与自我报告的刺激价值估计有关。最后,额叶和顶叶皮层的亚区代表了竞争选择的不同价值,并可能向偏向空间选择的视觉区域提供信号,以支持更有价值的刺激。
Economists and cognitive psychologists have long known that prior rewards bias decision making in favor of options with high expected value. Accordingly, value modulates the activity of sensorimotor neurons involved in initiating movements towards one of two competing decision alternatives. However, little is known about how value influences the acquisition and representation of incoming sensory information, or about the neural mechanisms that track the relative value of each available stimulus to guide behavior. Here, fMRI revealed value-related modulations throughout spatially selective areas of the human visual system in the absence of overt saccadic responses (including in V1). These modulations are primarily associated with the reward history of each stimulus and not to self-reported estimates of stimulus value. Finally, subregions of frontal and parietal cortex represent the differential value of competing alternatives and may provide signals to bias spatially-selective visual areas in favor of more valuable stimuli.
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