The influence of nonautonomous P elements on hybrid dysgenesis in Drosophila melanogaster.
The influence of nonautonomous P elements on hybrid dysgenesis in Drosophila melanogaster.
复制标题
非自主P元件对果蝇杂交发育不全的影响。
DOI:
10.1093/genetics/117.4.671
复制
发表时间:
1987
期刊:
影响因子:
3.3
通讯作者:
Zunt,JR
中科院分区:
文献类型:
--
作者:
Simmons,MJ;Raymond,JD;Boedigheimer,MJ;Zunt,JR
An inbred line of the M' strain Muller-5 Birmingham was studied for its abilities to affect P-M hybrid dysgenesis. This strain possesses 57Pelements, all of which are apparently defective in the production of the P transposase. In combination with transposase-producing elements, these nonautonomous elements can enhance or diminish the incidence of hybrid dysgenesis, depending on the trait that is studied. Dysgenic flies that have one or more paternally-derived chromosomes with these elements partially repress the instability of thePelement insertion mutation, snw; however, such flies have elevated frequencies of another dysgenic trait, GD sterility, and also show distorted segregation ratios. An explanation is presented in which all of these phenomena are unified as manifestations of the kinetics ofPelement activation in the germ line. The progeny of Muller-5 Birmingham females exhibit partial repression of both snwinstability and GD sterility. This repression appears to involve a factor that can be transmitted maternally through at least two generations. This mode of repression therefore conforms to the pattern of inheritance of the P cytotype, the condition that brings about nearly total repression ofPelement activity in some strains. Models in which this repression could arise from the nonautonomousPelements of Muller-5 Birmingham are discussed.
登录
查看更多内容
影响因子:
3.3
作者:
Daniels,SB;Clark,SH;Kidwell,MG;Chovnick,A
通讯作者:
Chovnick,A
影响因子:
64.5
作者:
BINGHAM, PM;KIDWELL, MG;RUBIN, GM
通讯作者:
RUBIN, GM
DOI:
10.1101/sqb.1981.045.01.072
发表时间:
1981
期刊:
Cold Spring Harbor symposia on quantitative biology
影响因子:
--
作者:
W. Engels
通讯作者:
W. Engels
DOI:
10.1002/em.2860010110
发表时间:
1979
期刊:
Environmental mutagenesis
影响因子:
--
作者:
W. Engels
通讯作者:
W. Engels