What is nausea? A historical analysis of changing views.
What is nausea? A historical analysis of changing views.
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DOI：
10.1016/j.autneu.2016.07.003
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发表时间：
2017-01
影响因子：
2.7
通讯作者：
Yates, Bill J.
中科院分区：
文献类型：
--
作者：
Balaban, Carey D.;Yates, Bill J.
几千年来，“恶心”的含义已经发生了变化。医学术语“恶心”源自古希腊术语 ναυτια 和 ναυσια，指定晕船的体征和症状。在古典文献中，恶心指的是一系列广泛的感知和行为，包括嗜睡和脱离、头痛（偏头痛）和厌食，并意识到只有在情况严重时才会出现呕吐。然而，最近的一些文章将定义限制为呕吐之前的感觉。恶心的定义很复杂，因为它有很多触发因素，并且可能缓慢或快速累积，因此前驱体征和症状可能会有所不同。特别是，被称为“索皮特综合征”的脱离反应通常仅在呕吐刺激具有中等刺激性时出现，并且不会很快达到呕吐或脱离触发事件的程度。这篇综述考虑了“恶心”的定义如何随着时间的推移而演变，并总结了呕吐之前发生的可能表明恶心的生理变化。还描述了在不同刺激下发生的恶心感知的差异以及伴随的生理反应。综合该信息以提供恶心的操作定义。
The connotation of “nausea” has changed across several millennia. The medical term ‘nausea’ is derived from the classical Greek terms ναυτια and ναυσια, which designated the signs and symptoms of seasickness. In classical texts, nausea referred to a wide range of perceptions and actions, including lethargy and disengagement, headache (migraine), and anorexia, with an awareness that vomiting was imminent only when the condition was severe. However, some recent articles have limited the definition to the sensations that immediately precede emesis. Defining nausea is complicated by the fact that it has many triggers, and can build-up slowly or rapidly, such that the prodromal signs and symptoms can vary. In particular, disengagement responses referred to as the “sopite syndrome” are typically present only when emetic stimuli are moderately provocative, and do not quickly culminate in vomiting or disengagement from the triggering event. This review considers how the definition of “nausea” has evolved over time, and summarizes the physiological changes that occur prior to vomiting that may be indicative of nausea. Also described are differences in the perception of nausea, as well as the accompanying physiological responses, that occur with varying stimuli. This information is synthesized to provide an operational definition of nausea.
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影响因子：
3.7
作者：
Balaban CD;Ogburn SW;Warshafsky SG;Ahmed A;Yates BJ
通讯作者：
Yates BJ
DOI：
10.1016/0165-1838(86)90009-3
发表时间：
1986-02-01
期刊：
JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM
影响因子：
--
作者：
BAHR, R;BARTEL, B;JANIG, W
通讯作者：
JANIG, W
DOI：
10.1152/ajpregu.2001.281.4.r1243
发表时间：
2001-10-01
影响因子：
2.8
作者：
Billig, I;Yates, BJ;Rinaman, L
通讯作者：
Rinaman, L
影响因子：
10.3
作者：
Balaban, CD;Jacob, RG
通讯作者：
Jacob, RG
影响因子：
5.3
作者：
Alhadeff, Amber L.;Holland, Ruby A.;De Jonghe, Bart C.
通讯作者：
De Jonghe, Bart C.