Relationship between plasma concentrations of β-carotene and α-tocopherol and life-style factors and levels of DNA adducts in lymphocytes
Relationship between plasma concentrations of β-carotene and α-tocopherol and life-style factors and levels of DNA adducts in lymphocytes
复制标题
血浆β-胡萝卜素和α-生育酚浓度与生活方式因素及淋巴细胞DNA加合物水平的关系
DOI：
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发表时间：
1997
期刊：
影响因子：
--
通讯作者：
K. Tomokuni
中科院分区：
文献类型：
--
作者：
Yanping Wang;M. Ichiba;H. Oishi;M. Iyadomi;N. Shono;K. Tomokuni
Abstract β‐Carotene and α‐tocopherol have been thought to reduce risk of lung cancer. Whether β‐carotene and α‐tocopherol influence human DNA adducts, indicators of biologically effective doses of carcinogens, has been seldom studied. In this cross‐sectional study, we measured plasma β‐carotene and CL‐tocopherol in 192 healthy men and DNA adducts in lymphocytes in 104 of the subjects. Because genetic polymorphism ofcytochrome P‐4501A1 (CYP1A1) and glutathione S‐transferase M1 (GSTM1) has been associated with interference information of reactive intermediates and detoxification of polycyclic aromatic hydrocarbons, we also obtained data concerning genetic polymorphism of CYPIAI and GSTM1. In multiple regression analysis, parameters such as alcohol consumed per day, high‐density lipoprotein cholesterol, Quetelet index, and cigarettes smoked per day were correlated inversely, whereas age, plasma α‐tocopherol, and intake frequency of fruits were correlated positively with plasma β‐carotene concentration. DNA a...
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缺乏维生素 E 的鳟鱼和大鼠肝微粒体中脂质过氧化、抗氧化酶和致癌物代谢的变化。
影响因子：
3.8
作者：
Williams,DE;Carpenter,HM;Buhler,DR;Kelly,JD;Dutchuk,M
通讯作者：
Dutchuk,M
DOI：
10.1093/jnci/86.1.33
发表时间：
1994-01-05
期刊：
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子：
--
作者：
MAYNE, ST;JANERICH, DT;MCKNEALLY, MF
通讯作者：
MCKNEALLY, MF
维生素 E 增强雪貂体内 β-胡萝卜素的淋巴运输及其向维生素 A 的转化。
影响因子：
29.4
作者：
Wang,XD;Marini,RP;Hebuterne,X;Fox,JG;Krinsky,NI;Russell,RM
通讯作者：
Russell,RM
DOI：
10.1056/nejm199404143301501
发表时间：
1994-04-14
期刊：
The New England journal of medicine
影响因子：
--
作者：
通讯作者：
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β-胡萝卜素介导的对小鼠乳腺中 7,12-二甲基苯并（a）蒽和 7-羟甲基-12-甲基苯（a）蒽诱导的 DNA 加合物的抑制作用。
DOI：
10.1016/0959-8049(92)90470-m
发表时间：
1992
期刊：
European journal of cancer (Oxford, England : 1990)
影响因子：
--
作者：
Das,SK;Jia,TZ;Bandyopadhyay,AM;Banerjee,MR
通讯作者：
Banerjee,MR