In situ monitoring of single molecule binding reactions with time-lapse atomic force microscopy on functionalized DNA origami.
In situ monitoring of single molecule binding reactions with time-lapse atomic force microscopy on functionalized DNA origami.
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使用延时原子力显微镜对功能化 DNA 折纸上的单分子结合反应进行原位监测。
DOI:
10.1039/c1nr10181a
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发表时间:
2011-06
期刊:
影响因子:
6.7
通讯作者:
Li, Bin*
中科院分区:
文献类型:
--
作者:
Wu, Na;Zhou, Xingfei;Czajkowsky, Daniel M.;Ye, Ming;Zeng, Dongdong;Fu, Yanming;Fan, Chunhai;Hu, Jun;Li, Bin*
Individual biomolecular binding events were recorded in situ by combining time-lapse atomic force microscopy and DNA origami. Single streptavidin molecules bound to specifically biotinyated DNA origami were simply counted as a function of time to obtain a direct measure of the binding rate.
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影响因子:
15
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通讯作者:
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影响因子:
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通讯作者:
Hinterdorfer, P
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14.9
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Shlyakhtenko, LS;Potaman, VN;Lyubchenko, YL
通讯作者:
Lyubchenko, YL