Patterns of alcohol use among early head and neck cancer survivors: A cross-sectional survey study using the alcohol use disorders identification test (AUDIT).
Patterns of alcohol use among early head and neck cancer survivors: A cross-sectional survey study using the alcohol use disorders identification test (AUDIT).
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DOI：
10.1016/j.oraloncology.2021.105328
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发表时间：
2021-08
期刊：
影响因子：
4.8
通讯作者：
Diefenbach, Michael A.
中科院分区：
文献类型：
--
作者：
Teckie, Sewit;Wotman, Michael;Marziliano, Allison;Orner, David;Yi, Jungen;Mulvany, Colm;Ghaly, Maged;Parashar, Bhupesh;Diefenbach, Michael A.
头颈癌 (HNC) 幸存者的饮酒会对患者的预后产生负面影响，并且是复发性和第二原发性肿瘤的重要危险因素。尽管多个癌症协会提出了建议，但饮酒仍然是该人群的一个常见问题。使用酒精使用障碍识别测试 (AUDIT) 自我报告问卷进行横断面研究。 HNC 患者在治疗后至少 2 年内每 3-6 个月完成一次治疗前和随访预约的调查。 796 项调查可供分析。大多数参与者是男性（75.7%），患有口咽癌（34.5%）或喉癌（16.7%）。饮酒者的比例从治疗前的 56.1% 下降至治疗后 0-3 个月的 40.4%，但随后增加并在治疗后 24 个月以上超过基线水平（64.4%，p = 0.0079）。同时，适度饮酒者（AUDIT = 1 – 3）从治疗前的 34.2% 下降至治疗后 0-3 个月的 25.2%，但随后在治疗后 24 个月以上增加并超过基线水平（39.7%，p = 0.0129）。重度饮酒者 (AUDIT > 3) 和最重度饮酒者 (AUDIT > 6) 的趋势相似，但不具有统计显着性。治疗后 24 个多月时，我们观察到女性使用者（39.1% 至 63.2%，p = 0.0213）和 55 岁以下适度饮酒者（43.4% 至 61.9%，p = 0.0184）的统计显着增加。 HNC 幸存者的饮酒量在治疗后的几个月内短暂减少，但随后增加，并在 24 个月内基本保持稳定。这种模式尤其令人担忧，并凸显了及时干预的必要性。
Alcohol use among survivors of head and neck cancer (HNC) negatively impacts patient outcomes and is an important risk factor for recurrent and second primary tumors. Despite recommendations from several cancer societies, alcohol consumption remains a common problem in this population. A cross-sectional study was performed with the Alcohol Use Disorders Identification Test (AUDIT) Self- Report questionnaire. Patients with HNC completed surveys at pre-treatment and follow-up appointments every 3–6 months for at least 2-years after treatment. 796 surveys were available for analysis. Most participants were male (75.7%) and had either oropharyngeal (34.5%) or laryngeal (16.7%) cancer. The percentage of alcohol drinkers decreased from 56.1% at pre- treatment to 40.4% at 0–3 months post-treatment, but then increased and surpassed baseline levels by 24 + months post-treatment (64.4%, p = 0.0079). Concurrently, moderate drinkers (AUDIT = 1 – 3) decreased from 34.2% at pre-treatment to 25.2% at 0–3 months post-treatment, but then increased and surpassed baseline levels at 24 + months post-treatment (39.7%, p = 0.0129). Trends among heavy (AUDIT > 3), and heaviest (AUDIT > 6) drinkers were similar, but not statistically significant. At 24 + months post-therapy, we observed a statistically significant increase in female users (39.1% to 63.2%, p = 0.0213) and moderate drinkers < 55 years old (43.4% to 61.9%, p = 0.0184). Alcohol consumption in survivors of HNC transiently decreases in the immediate months after treatment, but then increases and remains largely stable by 24 months. This pattern is particularly concerning and highlights the need for timely interventions.
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DOI：
10.1016/s0140-6736(18)32203-7
发表时间：
2018-11-10
期刊：
Lancet (London, England)
影响因子：
--
作者：
GBD 2017 Causes of Death Collaborators
通讯作者：
GBD 2017 Causes of Death Collaborators
DOI：
10.6004/jnccn.2019.7341
发表时间：
2020-01-01
影响因子：
13.4
作者：
Sanford, Nina N.;Sher, David J.;Mahal, Brandon A.
通讯作者：
Mahal, Brandon A.
影响因子：
45.3
作者：
Gritz, ER;Carmack, CL;Abemayor, E
通讯作者：
Abemayor, E
影响因子：
13.6
作者：
Leoncini E;Vukovic V;Cadoni G;Giraldi L;Pastorino R;Arzani D;Petrelli L;Wünsch-Filho V;Toporcov TN;Moyses RA;Matsuo K;Bosetti C;La Vecchia C;Serraino D;Simonato L;Merletti F;Boffetta P;Hashibe M;Lee YA;Boccia S
通讯作者：
Boccia S
影响因子：
3.4
作者：
Simcock, R.;Simo, R.
通讯作者：
Simo, R.