Simulating human cardiac electrophysiology on clinical time-scales.
Simulating human cardiac electrophysiology on clinical time-scales.
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DOI:
10.3389/fphys.2011.00014
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发表时间:
2011
影响因子:
4
通讯作者:
Plank G
中科院分区:
文献类型:
--
作者:
Niederer S;Mitchell L;Smith N;Plank G
In this study, the feasibility of conducting in silico experiments in near-realtime with anatomically realistic, biophysically detailed models of human cardiac electrophysiology is demonstrated using a current national high-performance computing facility. The required performance is achieved by integrating and optimizing load balancing and parallel I/O, which lead to strongly scalable simulations up to 16,384 compute cores. This degree of parallelization enables computer simulations of human cardiac electrophysiology at 240 times slower than real time and activation times can be simulated in approximately 1 min. This unprecedented speed suffices requirements for introducing in silico experimentation into a clinical workflow.
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DOI:
10.1196/annals.1380.023
发表时间:
2006-01-01
期刊:
INTERACTIVE AND INTEGRATIVE CARDIOLOGY
影响因子:
--
作者:
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影响因子:
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DOI:
10.1016/j.pbiomolbio.2007.07.012
发表时间:
2008-01
影响因子:
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作者:
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通讯作者:
Plank G
影响因子:
37.8
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