Feasibility of a randomized trial of a high-vegetable diet to prevent breast cancer recurrence.
Feasibility of a randomized trial of a high-vegetable diet to prevent breast cancer recurrence.
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高蔬菜饮食预防乳腺癌复发的随机试验的可行性。
DOI：
10.1080/01635589709514589
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发表时间：
1997
期刊：
影响因子：
--
通讯作者：
E. Greenberg
中科院分区：
文献类型：
--
作者：
J. Pierce;S. Faerber;F. A. Wright;V. Newman;S. Flatt;S. Kealey;C. Rock;W. Hryniuk;E. Greenberg
流行病学证据支持饮食影响乳腺癌风险的概念，并表明乳腺癌诊断后的预后也可能与可改变的营养因素有关。本研究的目的是调查一项高蔬菜、低脂肪和高纤维饮食干预的随机试验的可行性，以降低乳腺癌幸存者的复发风险。通过密集的电话咨询促进了饮食模式的这一重大变化。参与者是93名在过去四年内被诊断患有乳腺癌（I期，II期和IIIA期）并已完成初步治疗的女性。我们在6个月和12个月时使用重复的24小时饮食回忆和循环类胡萝卜素浓度的测量来评估对研究饮食的依从性。随机分组后6个月，与对照组相比，干预组的蔬菜（+4.6份/天）、水果（+0.7份/天）和纤维（+6.4 g/1,000 kcal）的平均摄入量显著增加，膳食脂肪的摄入量显著减少（能量的-9.9%）。干预组的循环类胡萝卜素浓度也增加了。这些变化在12个月访视时持续存在。这项研究的结果表明，电话咨询可以是一个有用的方法，在饮食干预和乳腺癌幸存者可以采取和保持高蔬菜，减少脂肪的饮食模式。
Epidemiologic evidence supports the concept that diet influences risk for breast cancer and suggests that prognosis after the diagnosis of breast cancer may also be related to modifiable nutritional factors. The purpose of this study was to investigate the feasibility of a randomized trial of a high-vegetable, reduced-fat, and increased-fiber diet intervention to reduce risk for recurrence among breast cancer survivors. This major change in dietary pattern was promoted through intensive telephone counseling. Participants were 93 women who had been diagnosed with breast cancer (stages I, II, and IIIA) within the previous four years and who had completed their initial treatment. We assessed adherence to the study diet using repeated 24-hour dietary recalls at 6 and 12 months and measurement of circulating carotenoid concentrations. Six months after randomization, the intervention group had significantly increased their mean intake of vegetables (+4.6 servings/day), fruit (+0.7 servings/day), and fiber (+6.4 g/1,000 kcal) and significantly reduced their intake of dietary fat (-9.9% of energy) compared with the control group. Circulating concentrations of carotenoids also increased in the intervention group. These changes persisted at the 12-month visit. Results of this study demonstrate that telephone counseling can be a useful approach in diet intervention and that breast cancer survivors can adopt and maintain a high-vegetable, reduced-fat dietary pattern.
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影响因子：
7.1
作者：
Yeum, KJ;Booth, SL;Russell, RM
通讯作者：
Russell, RM
影响因子：
7.1
作者：
NIERENBERG, DW;NANN, SL
通讯作者：
NANN, SL
每天 5 颗，改善健康：一项新的研究计划。
影响因子：
--
作者：
Havas,S;Heimendinger,J;Reynolds,K;Baranowski,T;Nicklas,TA;Bishop,D;Buller,D;Sorensen,G;Beresford,SA;Cowan,A
通讯作者：
Cowan,A
血浆类胡萝卜素作为蔬菜和水果摄入量的生物标志物。
DOI：
--
发表时间：
1994
期刊：
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子：
--
作者：
Campbell,DR;Gross,MD;Martini,MC;Grandits,GA;Slavin,JL;Potter,JD
通讯作者：
Potter,JD
血浆类胡萝卜素作为蔬菜摄入量的生物标志物：明尼苏达大学癌症预防研究单位喂养研究。
DOI：
--
发表时间：
1995
期刊：
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子：
--
作者：
Martini,MC;Campbell,DR;Gross,MD;Grandits,GA;Potter,JD;Slavin,JL
通讯作者：
Slavin,JL