Comparison of serum levels of vitamin D in periodontitis patients with and without type 2 diabetes and healthy subjects.

Comparison of serum levels of vitamin D in periodontitis patients with and without type 2 diabetes and healthy subjects.
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DOI:
10.1002/cre2.657
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发表时间:
2022-12
影响因子:
1.8
通讯作者:
Raeesi, Vajehallah
Raeesi, Vajehallah
中科院分区:
其他
文献类型:
--
作者:
Akbari, Narjes;Bojd, Marjan Hanafi;Moghadam, Mahdjoube Goldani;Raeesi, Vajehallah

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本研究的目的是了解牙周炎合并和不合并2型糖尿病患者的血清维生素D水平,并与健康人进行比较。本研究选择符合入选条件的48例牙周炎合并2型糖尿病患者、53例牙周炎患者(P组)和42例年龄在30~50岁的对照组。测量菌斑指数、牙石指数、改良牙龈指数、牙槽深度、临床附着丧失(CAL)和牙齿脱落。采用电化学发光免疫法测定血清25(OH)D水平,生化比色法测定空腹血糖和糖化血红蛋白。血清25(OH)D水平分别为17.06 ± 10.73,15.12 ± 7.74,14.17 ± 11.04 ηg/ml,差异无统计学意义。与其他组相比,糖尿病患者的平均CAL显著升高。与对照组相比,牙周炎患者的糖尿病前期患病率显著升高。在被研究的人群中,维生素D缺乏的患病率很高。血清25(OH)D水平组间差异无统计学意义。牙周炎患者患糖尿病的风险增加。
The purpose of this study is to find out the levels of serum vitamin D in periodontitis patients with and without type 2 diabetes and to compare them with healthy subjects. In this study, 48 periodontitis patients with type 2 diabetes mellitus (PDM), 53 periodontitis patients (P), and 42 controls who were in the age ranges of 30–50 years and had the entry requirements were selected. Plaque index, calculus index, modified gingival index, pocket depth, clinical attachment loss (CAL), and tooth loss were measured. Serum 25(OH)D level was estimated by electrochemiluminescence immunoassay, and fasting blood sugar and glycosylated hemoglobin were estimated by biochemical colorimetric assays. The mean serum 25(OH)D level was 17.06 ± 10.73, 15.12 ± 7.74, and 14.17 ± 11.04 ηg/ml for PDM, P, and control groups, respectively, showing no statistical difference. The mean CAL was significantly high in diabetic patients as compared to other groups. Prediabetes prevalence was significantly high in periodontitis patients as compared to controls. The prevalence of vitamin D insufficiency was high in the population studied. Serum levels of 25(OH)D showed no significant difference between groups. Periodontitis patients showed an elevated risk for diabetes.
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