Performance of shear wave elastography for differentiation of benign and malignant solid breast masses.
Performance of shear wave elastography for differentiation of benign and malignant solid breast masses.
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剪切波弹性成像区分良性和恶性实性乳腺肿块的性能
DOI：
10.1371/journal.pone.0076322
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Tang KF
中科院分区：
文献类型：
--
作者：
Li G;Li DW;Fang YX;Song YJ;Deng ZJ;Gao J;Xie Y;Yin TS;Ying L;Tang KF
目的进行一项评价剪切波弹性成像（SWE）识别乳腺恶性肿块能力的荟萃分析。方法检索PubMed、科克伦图书馆和ISI Web of Knowledge，以评价SWE识别恶性乳腺肿块的准确性。根据敏感性、特异性和分层汇总受试者工作特征（HSROC）曲线评价SWE的诊断准确性。还进行了分析，根据SWE模式使用：超声剪切成像（SSI）和声辐射力脉冲（ARFI）技术。应用Fagan图分析SWE对乳腺恶性肿块的诊断价值。结果共纳入9篇文献，包括1888名女性和2000个乳腺肿块。SSI的总体灵敏度和特异性分别为0.91（95%置信区间[CI]，0.88-0.94）和0.82（95% CI，0.75-0.87），ARFI的总体灵敏度和特异性分别为0.89（95% CI，0.81-0.94）和0.91（95% CI，0.84-0.95）。SSI和ARFI的HSROC分别为0.92（95% CI，0.90-0.94）和0.96（95% CI，0.93-0.97）。SSI和ARFI都是非常有用的，在“阳性”测量（超过阈值）后正确区分良性和恶性乳腺肿块的概率分别为83%和91%，在“阴性”测量（低于阈值）后，疾病的概率分别低至10%和11%，当预测试概率为50%时。结论SWE可作为乳腺肿块分型的良好工具。
Objectives To perform a meta-analysis assessing the ability of shear wave elastography (SWE) to identify malignant breast masses. Methods PubMed, the Cochrane Library, and the ISI Web of Knowledge were searched for studies evaluating the accuracy of SWE for identifying malignant breast masses. The diagnostic accuracy of SWE was evaluated according to sensitivity, specificity, and hierarchical summary receiver operating characteristic (HSROC) curves. An analysis was also performed according to the SWE mode used: supersonic shear imaging (SSI) and the acoustic radiation force impulse (ARFI) technique. The clinical utility of SWE for identifying malignant breast masses was evaluated using analysis of Fagan plot. Results A total of 9 studies, including 1888 women and 2000 breast masses, were analyzed. Summary sensitivities and specificities were 0.91 (95% confidence interval [CI], 0.88–0.94) and 0.82 (95% CI, 0.75–0.87) by SSI and 0.89 (95% CI, 0.81–0.94) and 0.91 (95% CI, 0.84–0.95) by ARFI, respectively. The HSROCs for SSI and ARFI were 0.92 (95% CI, 0.90–0.94) and 0.96 (95% CI, 0.93–0.97), respectively. SSI and ARFI were both very informative, with probabilities of 83% and 91%, respectively, for correctly differentiating between benign and malignant breast masses following a “positive” measurement (over the threshold value) and probabilities of disease as low as 10% and 11%, respectively, following a “negative” measurement (below the threshold value) when the pre-test probability was 50%. Conclusions SWE could be used as a good identification tool for the classification of breast masses.
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影响因子：
15.8
作者：
Moher D;Liberati A;Tetzlaff J;Altman DG;PRISMA Group
通讯作者：
PRISMA Group
影响因子：
1.3
作者：
Tozaki, Mitsuhiro;Fukuma, Eisuke
通讯作者：
Fukuma, Eisuke
影响因子：
19.7
作者：
Athanasiou, Alexandra;Tardivon, Anne;Neuenschwander, Sylvia
通讯作者：
Neuenschwander, Sylvia
DOI：
10.1186/bcr2787
发表时间：
2010
期刊：
Breast cancer research : BCR
影响因子：
--
作者：
Evans A;Whelehan P;Thomson K;McLean D;Brauer K;Purdie C;Jordan L;Baker L;Thompson A
通讯作者：
Thompson A
影响因子：
3.3
作者：
Schaefer, F. K. W.;Heer, I.;Schreer, I.
通讯作者：
Schreer, I.