Reliability and Validity of Pupillary Response During Dual-Task Balance in Parkinson Disease.
Reliability and Validity of Pupillary Response During Dual-Task Balance in Parkinson Disease.
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DOI：
10.1016/j.apmr.2020.08.008
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发表时间：
2021-03
影响因子：
4.3
通讯作者：
Devos H
中科院分区：
文献类型：
--
作者：
Kahya M;Lyons KE;Pahwa R;Akinwuntan AE;He J;Devos H
目的探讨帕金森病（PD）患者双任务平衡条件下瞳孔反应的信度和效度。横断面研究堪萨斯大学医学中心帕金森病和运动障碍中心共68名受试者（n=33名PD，n=35名健康对照）不适用瞳孔反应是主要的结果测量，在以下条件下测量：单任务平衡眼睛睁开;单任务平衡眼睛闭合;双任务眼睛睁开;双任务眼睛闭合。在每种情况下，美国国家航空航天局任务负荷指数（NASA-TLX）进行管理，以评估自我报告的认知工作量。为了检查瞳孔反应的重测信度，在两小时内对每个受试者施用两次条件。组内相关系数（ICC）被用来分析两组在每种条件下瞳孔反应的重测信度。Pearson r相关用于评估瞳孔反应对NASA-TLX的会聚效度。在几乎所有条件下，两组的重测信度都非常好（ICC > 0.75）。瞳孔反应与NASA-TLX无相关性。然而，精神需求增加（NASA-TLX的子项目之一）与PD患者瞳孔反应增加显著相关（r = 0.38，p = 0.03）。瞳孔反应表现出良好的重测信度和效度在双任务的个人与PD和健康对照组的平衡。总的来说，这些结果表明，瞳孔反应代表了PD患者在双任务平衡期间认知工作负荷的稳定指数。
To investigate the reliability and validity of pupillary response during dual-task balance conditions in individuals with Parkinson’s disease (PD). Cross-sectional study University of Kansas Medical Center Parkinson’s Disease and Movement Disorder Center A total of 68 subjects (n=33 PD, n=35 healthy controls) Not applicable Pupillary response was the main outcome measure which was measured during the following conditions: Single-task balance eyes open; single-task balance eyes occluded; dual-task eyes open; dual-task eyes occluded. After each condition, the National Aeronautics and Space Administration-Task Load Index (NASA-TLX) was administered to assess self-reported cognitive workload. To examine the test-retest reliability of the pupillary response, the conditions were administered twice for each subject within two hours. Intraclass correlation coefficients (ICC) were used to analyze the test-retest reliability of pupillary response in each condition for both groups. Pearson’s r correlation was used to assess the convergent validity of pupillary response against NASA-TLX. The test-retest reliability was excellent for both groups in almost all conditions (ICC > 0.75). There were no correlations between pupillary response and NASA-TLX. However, increased mental demand (one of the subitems of NASA-TLX) significantly correlated with increased pupillary response in individuals with PD (r = 0.38, p = 0.03). Pupillary response showed excellent test-retest reliability and validity during dual-task balance for individuals with PD and healthy controls. Overall, these results suggest that pupillary response represents a stable index of cognitive workload during dual-task balance in individuals with PD.
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影响因子：
11
作者：
HUGHES, AJ;DANIEL, SE;LEES, AJ
通讯作者：
LEES, AJ
DOI：
10.1155/2012/918719
发表时间：
2012
期刊：
Parkinson's disease
影响因子：
--
作者：
Kelly VE;Eusterbrock AJ;Shumway-Cook A
通讯作者：
Shumway-Cook A
影响因子：
2.9
作者：
Kuipers JR;Thierry G
通讯作者：
Thierry G
影响因子：
2.9
作者：
Kahya, Melike;Wood, Tyler A.;Devos, Hannes
通讯作者：
Devos, Hannes
影响因子：
4.8
作者：
Kahya M;Moon S;Lyons KE;Pahwa R;Akinwuntan AE;Devos H
通讯作者：
Devos H