The ABC-associated Immunosenescence and Lifestyle Interventions in Autoimmune Disease.
The ABC-associated Immunosenescence and Lifestyle Interventions in Autoimmune Disease.
复制标题
DOI:
10.2478/rir-2022-0021
复制
发表时间:
2022-10
期刊:
影响因子:
--
通讯作者:
Wu, Haijing
中科院分区:
文献类型:
--
作者:
Ruan, Pinglang;Wang, Susu;Yang, Ming;Wu, Haijing
Aging-associated immune changes, termed immunosenescence, occur with impaired robust immune responses. This immune response is closely related to a greater risk of development of autoimmune disease (AID), which results in increased levels of autoantibodies and increased morbidity and mortality. In addition, lifestyle-related risk factors play a pivotal role in AID, which may be probable via senescence-related immune cell subsets. Age-associated B cell (ABC) subsets have been observed in those who have rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and multiple sclerosis (MS). Here, this review aims to highlight the mechanisms of ABCs with lifestyle interventions in AID, especially how immunosenescence affects the pathogenesis of AID and the future of aging-associated lifestyle interventions in immunosenescence of AID.
登录
查看更多内容
影响因子:
4.3
作者:
Bao, Weijia;Xie, Maosheng;Ye, Yujin
通讯作者:
Ye, Yujin
DOI:
10.1146/annurev-cellbio-011620-034148
发表时间:
2020-10-06
影响因子:
11.3
作者:
Frasca D;Diaz A;Romero M;Garcia D;Blomberg BB
通讯作者:
Blomberg BB
影响因子:
64.5
作者:
Fontana L;Partridge L
通讯作者:
Partridge L
影响因子:
7.8
作者:
Fiorito G;Caini S;Palli D;Bendinelli B;Saieva C;Ermini I;Valentini V;Assedi M;Rizzolo P;Ambrogetti D;Ottini L;Masala G
通讯作者:
Masala G
影响因子:
20.3
作者:
Hao, Yi;O'Neill, Patrick;Cancro, Michael P.
通讯作者:
Cancro, Michael P.