The effect of apnea management on novel coronavirus infection: A study on patients with obstructive sleep apnea.
The effect of apnea management on novel coronavirus infection: A study on patients with obstructive sleep apnea.
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呼吸暂停管理对新型冠状病毒感染的影响：对阻塞性睡眠呼吸暂停患者的研究。
DOI：
10.1016/j.sleh.2020.09.003
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发表时间：
2021-03
期刊：
影响因子：
4.1
通讯作者：
Alemohammad ZB
中科院分区：
文献类型：
--
作者：
Najafi A;Sadeghniiat-Haghighi K;Akbarpour S;Samadi S;Rahimi B;Alemohammad ZB
在确诊阻塞性睡眠呼吸暂停（OSA）患者中评估2019冠状病毒病（COVID-19）的发生率以及阻塞性睡眠呼吸暂停（OSA）管理对COVID-19的影响。横截面电话访谈调查。学术睡眠实验室伊朗成年人，≥ 18岁，确诊OSA。在275名患有OSA的参与者中，20%（n = 55）被怀疑有COVID-19病史，但没有阳性检测，18%（n = 51）根据他们报告的症状或确认的阳性检测属于明确的COVID-19组。重度OSA（呼吸暂停低通气指数≥ 30）与确诊COVID-19的风险增加相关，与确诊COVID-19组中轻度OSA相比，比值比（OR）95%置信区间（95%CI）为2.31（0.87-5.55）。与接受确诊COVID-19治疗的患者相比，未接受OSA治疗的患者确诊COVID-19的OR（95%CI）为2.43（1.26-4.67）。健康组、疑似组和COVID-19组的总睡眠时间（TST）分别为354、340和320分钟; TST与COVID-19相关（P值= 0.04）。同样，健康组、疑似组和COVID-19组的睡眠效率（SE）评分分别为75.7、74.2和67.9%（P值= 0.005）;贝克抑郁评分分别为13.8、13.0和17.7（P值= 0.056）。OSA作为一种促炎性疾病，伴有多种合并症，可能是导致COVID-19发生的一个因素。在OSA患者中，更严重的OSA、未对OSA进行治疗以及更低的TST和SE与COVID-19患病率增加相关。
To assess the frequency of coronavirus disease-2019 (COVID-19) and the effect of obstructive sleep apnea (OSA) management on COVID-19 among patients with confirmed OSA. Cross-sectional telephone interview survey. Academic sleep labs. Iranian adults ≥ 18 years old with confirmed OSA. Among 275 participants with OSA, 20% (n = 55) were suspected to have history of COVID-19 but had no positive test, and 18% (n = 51) were in the definite COVID-19 group according to their reported symptoms or confirmed positive test. Having severe OSA (apnea hypopnea index ≥ 30) was associated with an increased risk of definite COVID-19, with an odds ratio (OR) with 95% confidence interval (95% CI) of 2.31 (0.87-5.55) compared to having mild OSA in definite COVID-19 group. Those not undergoing treatment for OSA had an OR (95% CI) of 2.43 (1.26-4.67) for definite COVID-19 compared to those accepting treatment in definite COVID-19 group. Total sleep times (TSTs) were 354, 340, and 320 minutes in healthy, suspected, and COVID-19 groups, respectively; TST was associated with COVID-19 (P-value = .04). Similarly, sleep efficiency (SE) scores were 75.7, 74.2, and 67.9% for the healthy, suspected, and COVID-19 groups, respectively (P-value = .005); Beck Depression scores were 13.8, 13.0, and 17.7, respectively (P-value = .056). OSA as a proinflammatory condition with multiple comorbidities may be a contributing factor to developing COVID-19. Greater OSA severity, no treatment for OSA, and lower TST and SE were associated with increased COVID-19 prevalence among patients with OSA.
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影响因子：
9.6
作者：
MILLMAN, RP;REDLINE, S;LEVINSON, PD
通讯作者：
LEVINSON, PD
DOI：
10.1007/s11325-017-1602-6
发表时间：
2018-03
期刊：
Sleep & breathing = Schlaf & Atmung
影响因子：
--
作者：
Staats R;Rodrigues R;Barros A;Bacelar-Nicolau L;Aguiar M;Fernandes D;Moreira S;Simões A;Silva-Santos B;Rodrigues JV;Barbara C;de Almeida AB;Moita LF
通讯作者：
Moita LF
影响因子：
3.8
作者：
Ciftci, TU;Kokturk, O;Bilgihan, A
通讯作者：
Bilgihan, A
影响因子：
168.9
作者：
Huang, Chaolin;Wang, Yeming;Cao, Bin
通讯作者：
Cao, Bin
影响因子：
5.6
作者：
Steiropoulos, Paschalis;Kotsianidis, Loannis;Bouros, Demosthenes
通讯作者：
Bouros, Demosthenes