Self-assembled nano-wire of an amphiphilic biodegradable oligosaccharide-based graft copolymer in water
Self-assembled nano-wire of an amphiphilic biodegradable oligosaccharide-based graft copolymer in water
复制标题
两亲性可生物降解低聚糖基接枝共聚物在水中的自组装纳米线
DOI：
10.1016/j.carbpol.2011.10.069
复制
发表时间：
2012-02
影响因子：
11.2
通讯作者：
He, Yu-Jian
中科院分区：
文献类型：
--
作者：
Guo, Cheng-Gong;Wang, Cai-Qi;Qiu, Xiong-Ying;Jiang, Ming-Wei;He, Yu-Jian
制备了一种两亲性可生物降解的低聚糖基接枝共聚物，并通过 IR、H NMR 和 GPC 进行了表征，其中每个疏水性聚（ε-己内酯）（PCL，平均长度 DP̩≈6）被控制接枝到短的水溶性麦芽七糖（MH，DP = 7）主链的 3 位羟基上。通过透射电子显微镜（TEM）和动态光散射（DLC）研究了具有短主链和受控支化结构的两亲性MH-g-PCL6共聚物在水中的自组装结构。具有独特不对称结构的接枝共聚物自组装成平均直径为76nm的线状胶束。纳米线的长度随着二甲基甲酰胺中初始共聚物浓度的增加而增加。因此，开发了一种利用水中两亲性低聚糖基接枝共聚物形成具有不同长度和有趣的生物可降解特性的自组装纳米线的新途径。还讨论了纳米线胶束可能的形成机制。
A kind of amphiphilic biodegradable oligosaccharide-based graft copolymer was prepared and characterized by IR, H NMR and GPC, in which each hydrophobic poly(ɛ-caprolactone) (PCL, average length DP¯≈6) was controlled grafted onto the 3-position hydroxyl group of the short and water soluble maltoheptaose (MH, DP=7) backbone. The self-assembled structures in water of the amphiphilic MH-g-PCL6copolymer with a short main chain and controlled branched structure were investigated by transmission electron microscopy (TEM) and dynamic light scattering (DLC). The graft copolymer with a unique asymmetric structure self-assembled into wire-like micelles with average diameters of 76nm. And the length of the nano-wire increased with increased initial copolymer concentration in dimethylformamide. Thus, a new route to form self-assembled nano-wires with different lengths and interesting biodegradable properties was developed using amphiphilic oligosaccharide-based graft copolymer in water. The possible formation mechanism of nano-wire micelles was also discussed.
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影响因子：
4.6
作者：
J. Jeong;H. Kang;S. Yang;Jong-Duk Kim
通讯作者：
J. Jeong;H. Kang;S. Yang;Jong-Duk Kim
影响因子：
--
作者：
Michael W. Neiser;S. Muth;U. Kolb;J. R. Harris;J. Okuda;Manfred Schmidt
通讯作者：
Michael W. Neiser;S. Muth;U. Kolb;J. R. Harris;J. Okuda;Manfred Schmidt
影响因子：
5.5
作者：
Kwang Hee Kim;J. Huh;W. Jo
通讯作者：
Kwang Hee Kim;J. Huh;W. Jo
影响因子：
6.2
作者：
Philippova, OE;Volkov, EV;Rinaudo, M
通讯作者：
Rinaudo, M
DOI：
10.1002/pola.20100
发表时间：
2004-06
期刊：
Journal of Polymer Science Part A
影响因子：
--
作者：
C. Nouvel;P. Dubois;E. Dellacherie;J. Six
通讯作者：
C. Nouvel;P. Dubois;E. Dellacherie;J. Six