Health-related quality of life and survival in Chinese patients with chronic liver disease.
Health-related quality of life and survival in Chinese patients with chronic liver disease.
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DOI：
10.1186/1477-7525-11-131
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发表时间：
2013-08-01
影响因子：
3.6
通讯作者：
Hao JY
中科院分区：
文献类型：
--
作者：
Gao F;Gao R;Li G;Shang ZM;Hao JY
目的探讨中国慢性肝病(CLD)患者健康相关生活质量(HRQOL)与生存的关系。采用简表36中文版(SF-36)测量患者的HRQOL。在基线和18个月随访后收集SF-36评分、人口学和临床数据。数据的解释采用Kaplan-Meier和Cox比例风险回归生存分析。在分析中对存活的患者进行了审查。共纳入415例慢性阻塞性肺疾病患者和86例健康对照。在随访期内，50名患者死亡。健康对照组和存活患者的SF-36评分均高于死亡患者。健康对照组、存活患者和死亡患者的躯体成分总分分别为54.1 ± 5.2、48.9 ± 7.7和33.5 ± 8.2(p <； 0.001)。健康对照组、存活组和死亡组的心理成分总分分别为56.6 ± 8.2、53.0 ± 5.6和37.1 ± 12.1(p <； 0.001)。存活率与PCS和MCS评分以及腹水的存在显著相关。高质量生活质量与慢性阻塞性肺疾病患者的生存相关。PCS和MCS评分是生存的预测因子。
To investigate the relationship between health-related quality of life (HRQOL) and survival in Chinese patients with chronic liver disease (CLD). HRQOL was measured with the Chinese version of Short Form 36 (SF-36). SF-36 scores, demographic and clinical data were collected at baseline and after 18 months follow-up. Kaplan-Meier and Cox Proportional Hazard Regression survival analyses were used for interpretation of data. Surviving patients were censored in the analyses. A total of 415 Chinese patients with CLD and 86 healthy controls were enrolled. During the follow-up period 50 patients died. SF-36 scores in healthy controls and surviving patients were higher compared with those in deceased patients. Scores of physical component summary (PCS) in healthy controls, surviving and deceased patients were 54.1 ± 5.2, 48.9 ± 7.7 and 33.5 ± 8.2 respectively (p < 0.001). Scores of mental component summary (MCS) in healthy controls, surviving and deceased patients were 56.6 ± 8.2, 53.0 ± 5.6 and 37.1 ± 12.1 (p < 0.001) respectively. Survival was significantly associated with PCS and MCS scores, and the presence of ascites. HRQOL was associated with survival in patients with CLD. PCS and MCS scores were predictors of survival.
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影响因子：
7.2
作者：
Ünal, G;de Boer, JB;de Man, RA
通讯作者：
de Man, RA
影响因子：
2.4
作者：
van der Plas SM;Hansen BE;de Boer JB;Stijnen T;Passchier J;de Man RA;Schalm SW
通讯作者：
Schalm SW
DOI：
10.3350/kjhep.2009.15.s6.s40
发表时间：
2009-12-01
期刊：
The Korean journal of hepatology
影响因子：
--
作者：
Jang, Jeong Won
通讯作者：
Jang, Jeong Won
影响因子：
3.5
作者：
Steel, Jennifer L.;Chopra, Kapil;Carr, Brian I.
通讯作者：
Carr, Brian I.
影响因子：
4.3
作者：
Lam, Elegance Ting Pui;Lam, Cindy Lo Kuen;Fong, Daniel Yee Tak
通讯作者：
Fong, Daniel Yee Tak