An interrupted time series evaluation of a hepatitis C intervention for persons with HIV.
An interrupted time series evaluation of a hepatitis C intervention for persons with HIV.
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DOI：
10.1007/s10461-010-9870-1
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发表时间：
2011-11
影响因子：
4.4
通讯作者：
Muir, Andrew J.
中科院分区：
文献类型：
--
作者：
Proeschold-Bell, Rae Jean;Hoeppner, Bettina;Taylor, Baishakhi;Cohen, Sarah;Blouin, Rachel;Stringfield, Beth;Muir, Andrew J.
Accurate HCV knowledge is lacking among high-risk groups, including people with HIV/AIDS (PLWHA). Liver disease primarily due to HCV has emerged as a serious cause of mortality among PLWHA. We used an interrupted time series design to evaluate a social-ecologically based intervention for PLWHA, where an infectious disease clinic serving a six-county intervention area was monitored before (7 months) and after (17 months) intervention onset. The intervention included education of PLWHA and medical providers, HIV/HCV support groups and resource guides, and adaptation of the patient chart top sheet to include HCV test information. Clinic-level outcomes were assessed prospectively every other week for two years by interviewing patients (n=259) with clinic appointments on assessment days. Abrupt, gradual and delayed intervention effects were tested. Weighted regression analyses showed higher average HCV knowledge and a higher prevalence of patients reporting HCV discussion with their medical providers after intervention onset. A delayed effect was found for HCV awareness, and a gradually increasing effect was found for knowing one‘s HCV status. Other communities may consider adopting this intervention. Additional HCV interventions for PLWHA with HIV are needed.
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