Is the visceral adiposity index a potential indicator for the risk of kidney stones?
Is the visceral adiposity index a potential indicator for the risk of kidney stones?
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DOI：
10.3389/fendo.2022.1065520
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发表时间：
2022
影响因子：
5.2
通讯作者：
Hao, Zongyao
中科院分区：
文献类型：
--
作者：
Hou, Bingbing;Shen, Xudong;He, Qiushi;Chen, Yang;Xu, Yuexian;Chen, Mingwei;Xi, Junhua;Hao, Zongyao
为了确定内脏肥胖指数(VAI)是否与具有代表性的美国成年人患肾结石(KS)的风险有关。我们调查了59842名参加2007年至2018年国民健康与营养调查的参与者。通过Logistic回归分析确定内脏肥胖指数(VAI)与KS之间的关系。同时，亚组分析以及剂量−反应曲线的计算也被用来识别敏感组。29384名参与者的数据可用，其中包括2781名自我报告曾经历过KS疾病的人。总体而言，KS组VAI为0.74(0.70，0.78)，对照组为0.55(0.52，0.57)。调整混杂因素后，VAI每增加1个单位，KS患病率增加13%(OR=1.13，95%CI：1.08，1.19)。此外，VAI与KS患病率之间存在线性关系。亚组分析发现，男性(OR=1.14，95%CI：1.07，1.22)、女性(OR=1.14，95%CI：1.05，1.24)、白人(OR=1.20，95%CI：1.11，1.28)和其他种族、所有年龄亚组、非高血压(OR=1.06，95%CI：1.08，1.25)和非糖尿病(OR=1.14，95%CI：1.07，1.21)均与KS的危险性呈正相关。在具有代表性的美国成年人中，VAI升高与KS密切相关，这可能是肾结石风险的一个有前途的指标。
To determine whether the visceral adiposity index (VAI) was linked to the risk of kidney stones (KS) in the representative U.S. adults. We investigated 59842 participants who joined the 2007–2018 National Health and Nutrition Examination Survey. The association between the visceral adiposity index (VAI) and KS was identified by logistic regression analysis. Meanwhile, the subgroup analysis as well as the calculation of dose−response curves were also utilized to identify sensitive groups. Data from 29384 participants were available, including 2781 self-reported ever experiencing KS diseases. Overall, the VAI was 0.74 (0.70, 0.78) in the KS group, while 0.55 (0.52, 0.57) in the control group. After adjusting for confounders, the prevalence of KS increased by 13% for each unit of VAI increment (OR = 1.13, 95% CI: 1.08, 1.19). Moreover, a linear relationship was found between the VAI and the prevalence of KS. By subgroup analysis, we found that a positive correlation between VAI and the risk of KS both in male (OR=1.14, 95%CI:1.07, 1.22) and female (OR=1.14, 95%CI:1.05, 1.24), White (OR=1.20, 95%CI:1.11, 1.28) and other race, all aged subgroups, nonhypertensive (OR=1.06, 95%CI:1.08, 1.25) and nondiabetic subgroups (OR=1.14, 95%CI:1.07, 1.21). Elevated VAI was strongly associated with KS in representative U.S. adults, which may be a promising indicator for the risk of kidney stones.
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