Significantly increased visceral adiposity index in prehypertension.
Significantly increased visceral adiposity index in prehypertension.
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DOI：
10.1371/journal.pone.0123414
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Qu Q
中科院分区：
文献类型：
--
作者：
Ding Y;Gu D;Zhang Y;Han W;Liu H;Qu Q
中国高血压前期患病率上升，高血压前期经常在短时间内进展为高血压，已成为公共卫生问题。因此，本研究旨在探讨中国的内脏脂肪指数与血压的关系。采用分层随机整群抽样的方法，对中国进行横断面流行病学调查。不同性别的VAI四分位数截断点分别为：男性0.88、1.41、2.45，女性0.85、1.33、2.22。高血压前期和高血压的定义都是根据高血压预防、检测、评估和治疗联合国家委员会(JNC7)指南的第七次报告。采用多因素Logistic回归分析VAI与高血压前期、高血压之间的关系。在调整了年龄、教育程度、吸烟习惯、饮酒、体力活动、血肌酐、空腹血糖和血浆胰岛素后，男性高血压前期和高血压的OR值分别为1.514(1.074~2.133)，P=0.018和1.660(1.084~2.542)，P=0.020。在进一步调整上述混杂因素、慢性肾脏疾病和糖尿病后，男性高血压前期和高血压的OR值分别为1.660 1.533(1.086-2.165)，P=0.015和1.743(1.133-2.680)，P=0.011。在调整了年龄、教育程度、吸烟习惯、饮酒、体力活动、血肌酐、空腹血糖和血浆胰岛素后，女性高血压前期和高血压的OR值分别为1.691(1.223~2.338)，P=0.001和1.682(1.162~2.435)，P=0.006。在进一步调整上述混杂因素、慢性肾脏疾病和糖尿病后，女性高血压前期和高血压在VAI值上四分位数的OR值分别为1.688(1.220-2.334)和1.657(1.141-2.406)，P=0.008。在男性和女性中，较高的VAI与高血压前期和高血压均呈正相关。临床医生采取措施控制和预防内脏肥胖既是必要的，也是迫切的。
The prevalence of prehypertension has increased in China, and prehypertension frequently progress to hypertension over a short time period; both have become public health problems. Therefore, this study was conducted to determine the relationship between the Visceral Adiposity Index (VAI) and blood pressure (BP) in China. A cross-sectional epidemiological survey was conducted in China using a stratified random cluster sampling method. Sex-specific VAI quartile cut-off points were used as follows: 0.88, 1.41, 2.45 in males and 0.85, 1.33, 2.22 in females. Prehypertension and hypertension were each defined according to The Seventh Report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) guidelines. A multivariate logistic analysis was conducted to analyze the relationship among VAI, prehypertension and hypertension. The ORs for prehypertension and hypertension in the upper quartiles of the VAI were 1.514 (1.074-2.133), P=0.018 and 1.660 (1.084-2.542), P=0.020, in males, after adjusting for age, education, smoking habits, alcohol consumption, physical activity, serum creatinine, fasting glucose, and plasma insulin. Following further adjustments for the above confounders, chronic kidney disease, and diabetes, the ORs for prehypertension and hypertension in the upper quartile of the VAI were 1.660 1.533 (1.086-2.165), P=0.015, and 1.743 (1.133-2.680), P=0.011, in males. The ORs for prehypertension and hypertension in the upper quartile of the VAI were 1.691 (1.223-2.338), P=0.001, and 1.682 (1.162-2.435), P=0.006, in females, after adjusting for age, education, smoking habits, alcohol consumption, physical activity, serum creatinine, fasting glucose, and plasma insulin. Following further adjustments for the above confounders, chronic kidney disease, and diabetes, the ORs for prehypertension and hypertension in the upper quartile of the VAI were 1.688 (1.220-2.334), P=0.002, and 1.657 (1.141-2.406), P=0.008, in females. A higher VAI was positively associated with both prehypertension and hypertension in both males and females. It is both essential and urgent that clinicians take steps to control and prevent visceral adiposity.
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影响因子：
1.9
作者：
Knowles KM;Paiva LL;Sanchez SE;Revilla L;Lopez T;Yasuda MB;Yanez ND;Gelaye B;Williams MA
通讯作者：
Williams MA
影响因子：
4.5
作者：
Chen C;Xu Y;Guo ZR;Yang J;Wu M;Hu XS
通讯作者：
Hu XS
DOI：
10.1016/j.numecd.2014.07.006
发表时间：
2015-01
期刊：
Nutrition, metabolism, and cardiovascular diseases : NMCD
影响因子：
--
作者：
Du T;Zhang J;Yuan G;Zhang M;Zhou X;Liu Z;Sun X;Yu X
通讯作者：
Yu X
影响因子：
4.5
作者：
Amato MC;Giordano C;Pitrone M;Galluzzo A
通讯作者：
Galluzzo A
影响因子：
6.1
作者：
Amato, Marco Calogero;Verghi, Monica;Giordano, Carla
通讯作者：
Giordano, Carla