An anatomically realistic temperature phantom for radiofrequency heating measurements.
An anatomically realistic temperature phantom for radiofrequency heating measurements.
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DOI：
10.1002/mrm.25123
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发表时间：
2015-01
影响因子：
3.3
通讯作者：
Wald, Lawrence L.
中科院分区：
文献类型：
--
作者：
Graedel, Nadine N.;Polimeni, Jonathan R.;Guerin, Bastien;Gagoski, Borjan;Wald, Lawrence L.
具有逼真的电性能的拟人化幻象可以在兴奋期间更准确地繁殖组织电流模式。
幻影基于手工标记的解剖成像数据，由四个隔室组成，与相应的几何学和电性能中的相应人体组织相匹配。
以5 mm的各向同性分辨率获得了比0.1°C更好的全幻影的3D温度图，并获得了2-4分钟的采集时间。
我们的结果表明，具有复杂几何形状的解剖上逼真的幻象的可行性结合了幻影中的精确温度图。
An anthropomorphic phantom with realistic electrical properties allows for a more accurate reproduction of tissue current patterns during excitation. A temperature map can then probe the worst-case heating expected in the un-perfused case. We describe an anatomically realistic human head phantom that allows rapid 3D temperature mapping at 7 T. The phantom was based on hand-labeled anatomical imaging data and consists of four compartments matching the corresponding human tissues in geometry and electrical properties. The increases in temperature resulting from radiofrequency excitation were measured with MR thermometry using a temperature sensitive contrast agent (TmDOTMA−) validated by direct fiber optic temperature measurements. Acquisition of 3D temperature maps of the full phantom with a temperature accuracy better than 0.1°C was achieved with an isotropic resolution of 5 mm and acquisition times of 2–4 minutes. Our results demonstrate the feasibility of constructing anatomically realistic phantoms with complex geometries incorporating the ability to measure accurate temperature maps in the phantom. The anthropomorphic temperature phantom is expected to provide a useful tool for the evaluation of the heating effects of both conventional and parallel transmit pulses and help validate electromagnetic and temperature simulations.
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