Hormonal reactivity to MRI scanning in adolescents.
Hormonal reactivity to MRI scanning in adolescents.
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DOI：
10.1016/j.psyneuen.2009.03.006
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发表时间：
2009-09
影响因子：
3.7
通讯作者：
Pollak, Seth D.
中科院分区：
文献类型：
--
作者：
Eatough, Erin M.;Shirtcliff, Elizabeth A.;Hanson, Jamie L.;Pollak, Seth D.
磁共振成像（MRI）是一种现在广泛用于研究儿童和青少年情绪和认知过程的程序。然而，收集脑成像数据的背景是可能引起焦虑和压力的社会背景。有几种激素被证明对环境压力有反应。这些应激反应可能会影响成功完成手术或收集成像数据的能力。为了调查这些问题，我们测量了唾液皮质醇，脱氢表雄酮（DHEA），睾酮在160名青少年在模拟（实践）和实际的MRI。激素都对MRI扫描有反应，这表明MRI扫描本身可以引起应激反应，一些激素预测青少年可以成功完成扫描的可能性。模拟扫描并没有阻碍荷尔蒙对实际MRI的反应。这些数据表明，研究人员应该考虑的影响，提高激素反应的扫描环境，青少年的大脑成像的反应可能会导致图像数据丢失，并可能影响结果的措施。
Magnetic resonance imaging (MRI) is a procedure that is now widely used to study emotional and cognitive processes in children and adolescents. However, the context within which brain imaging data are collected is a social context that may induce anxiety and stress. Several hormones have been shown to be responsive to environmental stressors. These stress responses may impact ability to successfully complete the procedure or collect imaging data. To investigate these issues, we measured salivary cortisol, dehydroepiandrosterone (DHEA), and testosterone in 160 adolescents during both a simulation (practice) and actual MRI. Hormones were all responsive to the MRI scan, indicating that an MRI scan itself can induce a stress response, with some hormones predicting the likelihood that an adolescent could successfully complete the scan with adequate data. The simulation scan did not hinder hormonal responses to the actual MRI. These data suggest that researchers should consider the effects of heightened hormonal reactivity to the scanning environment; adolescent’s reactions to brain imaging may contribute to image data loss and may potentially influence outcome measures.
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DOI：
10.1097/00004583-199706000-00024
发表时间：
1997-06-01
影响因子：
13.3
作者：
Rosenberg, DR;Sweeney, JA;Thulborn, KR
通讯作者：
Thulborn, KR
影响因子：
2.5
作者：
Grey, SJ;Price, G;Mathews, A
通讯作者：
Mathews, A
影响因子：
3.5
作者：
BOOTH, A;SHELLEY, G;KITTOK, R
通讯作者：
KITTOK, R
影响因子：
10.6
作者：
Pruessner, Jens C.;Declovic, Katarina;Lupien, Sonia
通讯作者：
Lupien, Sonia
影响因子：
2.7
作者：
van Stegeren, Anda H.;Wolf, Oliver T.;Rombouts, Serge A. R. B.
通讯作者：
Rombouts, Serge A. R. B.