Early vascular response of ultra-thin bioresorbable polymer sirolimus-eluting stents assessed by optical frequency domain imaging: the EVALUATION study
Early vascular response of ultra-thin bioresorbable polymer sirolimus-eluting stents assessed by optical frequency domain imaging: the EVALUATION study
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通过光频域成像评估超薄生物可吸收聚合物西罗莫司洗脱支架的早期血管反应：评估研究
DOI：
10.1007/s12928-020-00689-9
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发表时间：
2020
影响因子：
3.2
通讯作者：
Kuwahara Koichiro
中科院分区：
文献类型：
--
作者：
Miura Takashi;Ueki Yasushi;Senda Keisuke;Otagiri Kyuhachi;Tachibana Takahiro;Saigusa Tatsuya;Ebisawa Soichiro;Motoki Hirohiko;Ikeda Uichi;Kuwahara Koichiro
本研究旨在应用光学频域成像技术(OFDI)评价超薄支架生物可吸收支架(BP-SES)的早期血管反应。与其他新一代超薄支架相比，超薄支架BP SES在疗效和安全终点方面具有卓越的疗效。然而，BP SES优于其他薄支撑型新一代支架的因素尚不清楚。来自3个心血管机构的32名需要在1个月进行分期手术的多支病变患者入选；其中31人立即接受了对外直接投资评估(n= ，31人)。所有患者在植入超薄支架BP SES后1个月进行评估。主端点是未覆盖的Struts的%。共分析了基线和经皮冠状动脉介入治疗后1个月的1723个横断面(17,014个支柱)。术后1个月的骨性假体裸露百分比为7.7%(4.0，13.8)。60-μm和80-μm支架的支架覆盖率分别为88.4%和80.4%(P= 0.013)，错位发生率分别为2.7%和4.3%(P=0.012)，差异有统计学意义。由于超薄支架的存在，超薄支架BP-SES植入有望实现早期血管反应。这可能最终导致较低的支架血栓形成和靶向病变失败率。UMIN000033406)。
This study aimed to evaluate the early vascular response of ultra-thin strut bioresorbable polymer sirolimus-eluting stents (BP SES) using optical frequency domain imaging (OFDI). Ultra-thin strut BP SES have superior outcomes in terms of efficacy and safety endpoints when compared to other thin strut new-generation stents. However, the factors contributing to the superiority of BP SES over other thin strut new-generation stents are unclear. A total of 32 patients with multivessel disease requiring staged procedures at 1 month were enrolled from 3 cardiovascular institutions; of these, 31 were immediately assessed by OFDI (n= 31). All patients were assessed at 1 month after ultra-thin strut BP SES implantation. The primary endpoint was % of uncovered struts. A total of 1723 cross sections (17,014 struts) were analyzed at baseline and 1 month after percutaneous coronary intervention. The % uncovered struts at 1-month follow-up was 7.7% (4.0, 13.8). Furthermore, the covered strut % (88.4% and 80.4%,P= 0.013) and malapposition rate (2.7% and 4.3%,P= 0.012) were significantly different between the 60-μm and 80-μm stents. Ultra-thin strut BP SES implantation may feasibly achieve early vascular responses due to the ultra-thin struts. This may ultimately lead to lower stent thrombosis and target lesion failure rates.Clinical trial registrationUniversity Hospital Medical Information Network Clinical Trials Registry (No. UMIN000033406).
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影响因子：
5.4
作者：
Zbinden R;Piccolo R;Heg D;Roffi M;Kurz DJ;Muller O;Vuilliomenet A;Cook S;Weilenmann D;Kaiser C;Jamshidi P;Franzone A;Eberli F;Jüni P;Windecker S;Pilgrim T
通讯作者：
Pilgrim T
影响因子：
37.8
作者：
Bangalore, Sripal;Toklu, Bora;Stone, Gregg W.
通讯作者：
Stone, Gregg W.
光学相干断层扫描引导的依维莫司洗脱支架植入治疗稳定型冠状动脉疾病的早期和中期血管反应。
DOI：
10.1016/j.cjca.2019.07.633
发表时间：
2019
期刊：
The Canadian journal of cardiology
影响因子：
--
作者：
T. Shinke;T. Itoh;M. Ishida;H. Otake;D. Terashita;T. Fusazaki;T. Kikuchi;T. Okamura;T. Morita;Takatoshi Hayashi;T. Sawada;Y. Yasaka;Takumi Inoue;Akira Matsuura;M. Kawata;A. Kozuki;J. Shite;T. Kataoka;K. Hibi;S. Ishihara;T. Akasaka;T. Kubo;Y. Ino;S. Sonoda;Jungo Furuya;Teppei Sugaya;Yoshisato Shibata;N. Kuriyama;N. Igarashi;Daisuke Matsumoto;Noritoshi Hiranuma;Yoritaka Otsuka;Y. Morino
通讯作者：
Y. Morino
影响因子：
4.8
作者：
Kitabata, Hironori;Kubo, Takashi;Akasaka, Takashi
通讯作者：
Akasaka, Takashi
DOI：
10.1016/j.ijcha.2018.08.001
发表时间：
2018-09
期刊：
International journal of cardiology. Heart & vasculature
影响因子：
--
作者：
Sato T;Taya Y;Suzuki N;Yuasa S;Kishi S;Koshikawa T;Fuse K;Fujita S;Ikeda Y;Kitazawa H;Takahashi M;Okabe M;Aizawa Y
通讯作者：
Aizawa Y