Design and dynamic characterization of "single-stroke" peristaltic PDMS micropumps.

Design and dynamic characterization of "single-stroke" peristaltic PDMS micropumps.
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DOI:
10.1039/c0lc00023j
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发表时间:
2011-01-21
期刊:
影响因子:
6.1
通讯作者:
Folch A
Folch A
中科院分区:
工程技术1区
文献类型:
--
作者:
Lai H;Folch A

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在本文中,我们提出了一种单片PDMS微泵,产生蠕动流,使用一个单一的控制通道,驱动一组不同大小的微阀。一个弹性体微阀的设计,提高了粘接的可靠性,被纳入微型泵。泵的性能进行评估的基础上,几个设计参数的大小,数量和连接的连续微阀沿着与控制通道的压力在各种工作频率。观察到的流速范围为0-5.87 μL min−1。这里展示的微泵设计代表了运行蠕动泵所需的控制线所占用的/真实的地产的数量的大幅减少,因此它应该成为高通量微流体中并行流体处理的广泛工具。
In this paper, we present a monolithic PDMS micropump that generates peristaltic flow using a single control channel that actuates a group of different-sized microvalves. An elastomeric microvalve design with a raised seat, which improves bonding reliability, is incorporated into the micropump. Pump performance is evaluated based on several design parameters—size, number, and connection of successive microvalves along with control channel pressure at various operating frequencies. Flow rates ranging 0–5.87 μL min−1 were observed. The micropump design demonstrated here represents a substantial reduction in the number of/real estate taken up by the control lines that are required to run a peristaltic pump, hence it should become a widespread tool for parallel fluid processing in high-throughput microfluidics.
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