Effects of the Laplace pressure on the cells during cytokinesis.

Effects of the Laplace pressure on the cells during cytokinesis.
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胞质分裂过程中拉普拉斯压力对细胞的影响

DOI:
10.1016/j.isci.2021.102945
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发表时间:
2021-09-24
期刊:
影响因子:
5.8
通讯作者:
Song F
Song F
中科院分区:
综合性期刊2区
文献类型:
--
作者:
Wang X;Li L;Shao Y;Wei J;Song R;Zheng S;Li Y;Song F

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拉普拉斯压力是决定细胞形态和功能的最基本的调节因素之一,因此受到了广泛的关注。在这里,我们系统地研究了在胞质分裂过程中拉普拉斯压力对细胞形态和功能的影响。我们发现,胞质分裂过程中的拉普拉斯压力可以直接控制细胞气泡的分布和大小,并通过改变细胞气泡的特性来调节细胞分裂的对称性。进一步,我们证明了拉普拉斯压力改变了细胞边界的结构一致性,从而调节了细胞分裂的对称性。我们的发现为拉普拉斯压力在胞质分裂过程中调节细胞分裂对称性的重要作用提供了进一步的见解。拉普拉斯压力控制细胞气泡的分布和大小拉普拉斯压力有助于形成更均匀的细胞边界拉普拉斯压力通过气泡细胞调节细胞分裂的对称性;细胞生物学的功能方面;生物物理学
The Laplace pressure is one of the most fundamental regulators that determine cell shape and function, and thus has been receiving widespread attention. Here, we systemically investigate the effect of the Laplace pressure on the shape and function of the cells during cytokinesis. We find that the Laplace pressure during cytokinesis can directly control the distribution and size of cell blebbing and adjust the symmetry of cell division by virtue of changing the characteristics of cell blebbing. Further, we demonstrate that the Laplace pressure changes the structural uniformity of cell boundary to regulate the symmetry of cell division. Our findings provide further insights as to the important role of the Laplace pressure in regulating the symmetry of cell division during cytokinesis. The Laplace pressure controls the distribution and size of cell blebbing The Laplace pressure helps to develop a more uniform cell boundary The Laplace pressure regulates symmetry of cell division by way of blebs Cell; Functional aspects of cell biology; Biophysics
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