Multiscale modeling for biologists.
Multiscale modeling for biologists.
复制标题
DOI：
10.1002/wsbm.33
复制
发表时间：
2009-07
影响因子：
7.9
通讯作者：
Klauschen, Frederick
中科院分区：
文献类型：
--
作者：
Meier-Schellersheim, Martin;Fraser, Iain D. C.;Klauschen, Frederick
Biomedical research frequently involves performing experiments and developing hypotheses that link different scales of biological systems such as, for instance, the scales of intracellular molecular interactions to the scale of cellular behavior and beyond to the behavior of cell populations. Computational modeling efforts that aim at exploring such multi-scale systems quantitatively with the help of simulations have to incorporate several different simulation techniques due to the different time and space scales involved. Here, we provide a non-technical overview of how different scales of experimental research can be combined with the appropriate computational modeling techniques. We also show that current modeling software permits building and simulating multi-scale models without having to become involved with the underlying technical details of computational modeling.
登录
查看更多内容
影响因子：
4.3
作者：
Efroni S;Harel D;Cohen IR
通讯作者：
Cohen IR
DOI：
10.1073/pnas.0712231105
发表时间：
2008-03-04
影响因子：
11.1
作者：
Izhikevich, Eugene M.;Edelman, Gerald M.
通讯作者：
Edelman, Gerald M.
影响因子：
5.8
作者：
Hucka, M;Finney, A;Wang, J
通讯作者：
Wang, J
影响因子：
56.9
作者：
Coggan, JS;Bartol, TM;Sejnowski, TJ
通讯作者：
Sejnowski, TJ
影响因子：
8.6
作者：
GRANER, F;GLAZIER, JA
通讯作者：
GLAZIER, JA