Declining Trends of Heart Rate Variability According to Aging in Healthy Asian Adults.
Declining Trends of Heart Rate Variability According to Aging in Healthy Asian Adults.
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DOI：
10.3389/fnagi.2020.610626
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发表时间：
2020
影响因子：
4.8
通讯作者：
Park MG
中科院分区：
文献类型：
--
作者：
Choi J;Cha W;Park MG
心率变异性（HRV）指数与衰老相关，并与自主神经系统有关。然而，亚洲人群的HRV随年龄的变化趋势尚未得到探讨。因此，我们提出了亚洲健康成人HRV指数随年龄增长而下降的线性回归模型。在韩国首尔，共有300名年龄在19-69岁的健康参与者（150名男性和150名女性）被分为5个年龄组：19-29岁、30-39岁、40-49岁、50 - 59岁和60 - 69岁，每组60人，测量HRV参数[高频（HF）、低频（LF）、甚低频（VLF）、总功率（TP）、HRV三角指数（HRV-index）、正常到正常区间的标准差（SDNN）和正常到正常区间大于50 ms的比例（pNN50）]。简单回归分析显示HRV指数随年龄的增长呈线性下降趋势。采用独立t检验调查各年龄组HRV值的性别差异。在健康的韩国成年人中，所有HRV指数随年龄的增长呈下降趋势，在西方人群中也是如此（所有指数P < 0.001）；HF （Y = - 0.039x + 6.833, R2 = 0.287）、LF （Y = - 0.047x + 7.197, R2 = 0.414）、VLF （Y = - 0.025x + 6.861, R2 = 0.177）、TP （Y = - 0.034x + 8.082, R2 = 0.352）、hrv指数（Y = - 0.125x + 15.628, R2 = 0.298）、SDNN （Y = - 0.502x + 53.907, R2 = 0.343）、pNN50 （Y = - 0.650x + 53.852, R2 = 0.345）均随年龄的增长而下降。两组HRV参数无明显性别差异。考虑健康亚洲人年龄的各种HRV指数的线性回归模型，可能有助于通过估计或跟踪亚洲人群的自主神经功能退化来预防与自主神经系统相关的疾病。
Heart rate variability (HRV) indices correlate with aging and are related to the autonomic nervous system. However, the trend of HRV with age has not been explored for the Asian population. Therefore, we proposed a linear regression model of HRV indices that decreased with aging in healthy Asian adults. HRV parameters [High frequency (HF), Low frequency (LF), Very low frequency (VLF), Total power (TP), HRV triangular index (HRV-index), Standard deviation of the normal-to-normal interval (SDNN), and Proportion of normal-to-normal intervals greater than 50 ms (pNN50)] were measured in a total of 300 healthy participants (150 men and 150 women) aged 19–69 years stratified into five age groups: 19–29, 30–39, 40–49, 50–59, and 60–69 years comprising 60 people each in Seoul, South Korea. A simple regression analysis was performed to reveal the linear declining trend of HRV indices with age. Independent t-tests were conducted to investigate the gender differences in HRV values depending on each age group. The values of all HRV indices showed a decreasing trend with age in healthy Korean adults, as observed in the Western population (P < 0.001 for all indices); HF (Y = −0.039x + 6.833, R2 = 0.287), LF (Y = −0.047x + 7.197, R2 = 0.414), VLF (Y = −0.025x + 6.861, R2 = 0.177), TP (Y = −0.034x + 8.082, R2 = 0.352), HRV-index (Y = −0.125x + 15.628, R2 = 0.298), SDNN (Y = −0.502x + 53.907, R2 = 0.343), and pNN50 (Y = −0.650x + 53.852, R2 = 0.345) all decreased with age. There was no significant gender difference in any HRV parameter. A linear regression model of various HRV indices has been presented considering the age of healthy Asians, which may be useful to prevent diseases related to the autonomic nervous system by estimating or tracking autonomic functional degeneration in the Asian population.
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DOI：
10.3390/diagnostics8030065
发表时间：
2018-09-10
期刊：
Diagnostics (Basel, Switzerland)
影响因子：
--
作者：
Liang Y;Chen Z;Ward R;Elgendi M
通讯作者：
Elgendi M
影响因子：
64.8
作者：
通讯作者：
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影响因子：
6.1
作者：
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通讯作者：
Ackermann-Liebrich, Ursula
DOI：
10.1016/j.bpobgyn.2013.02.005
发表时间：
2013-10
影响因子：
5.5
作者：
Lunenfeld, Bruno;Stratton, Pamela
通讯作者：
Stratton, Pamela
影响因子：
4.7
作者：
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