Classification of brain injury severity using a hybrid broadband NIRS and DCS instrument with a machine learning approach
Classification of brain injury severity using a hybrid broadband NIRS and DCS instrument with a machine learning approach
复制标题
使用混合宽带 NIRS 和 DCS 仪器以及机器学习方法对脑损伤严重程度进行分类
DOI:
10.1117/12.2670657
复制
发表时间:
2023
期刊:
影响因子:
--
通讯作者:
Bili D
中科院分区:
文献类型:
--
作者:
Bili D
Optical biomarkers of neonatal hypoxic ischemic (HI) brain injury can offer the advantage of continuous, cot-side assessment of the degree of injury; research thus far has focused on examining different optical measured brain physiological signals and feature combinations to achieve this. To maximize the breadth of physiological characteristics being taken into consideration, a multimodal optical platform has been developed, allowing unique physiological insights into brain injury. In this paper we present an assessment of severity of injury using a state-of-the-art hybrid broadband Near Infrared Spectrometer (bNIRS) and Diffusion Correlation Spectrometer (DCS) instrument called FLORENCE with a machine learning pipeline. We demonstrate in the preclinical neonatal model (the newborn piglet) that our approach can identify different HI insult severity (controls, mild, severe). We show that a machine learning pipeline based on k-means clustering can be used to differentiate between the controls and the HI piglets with an accuracy of 78%, the mild severity insult piglets from the severe insult piglets with an accuracy of 90% and can also differentiate the 3 piglet groups with an accuracy of 80%. So, this analytics pipeline demonstrates how optical data from multiple instruments can be processed towards markers of brain health.
登录
查看更多内容
DOI:
--
发表时间:
2020
期刊:
Definitions
影响因子:
--
作者:
Hilary E.A Whyte;Diane Wilson
通讯作者:
Diane Wilson
影响因子:
--
作者:
Gemma Bale;A. Oliver;I. Fierens;K. Broad;J. Hassell;G. Kawano;J. Rostami;G. Raivich;R. Sanders;N. Robertson;I. Tachtsidis
通讯作者:
I. Tachtsidis
影响因子:
4.6
作者:
Juan Wang;C. Guan;Jue Chen;K. Dou;Yida Tang;Weixian Yang;Yanpu Shi;F. Hu;L. Song;Jiansong Yuan;J. Cui;Min Zhang;Shuang Hou;Yongjian Wu;Yue;S. Qiao;Bo Xu
通讯作者:
Bo Xu
影响因子:
--
作者:
I. Tachtsidis;M. Tisdall;C. Pritchard;T. Leung;Arnab Ghosh;C. Elwell;Martin Smith
通讯作者:
Martin Smith
DOI:
10.1053/j.nainr.2011.07.004
发表时间:
2011-09-01
期刊:
Newborn and infant nursing reviews : NAINR
影响因子:
--
作者:
Allen KA;Brandon DH
通讯作者:
Brandon DH