The log-dynamic brain: how skewed distributions affect network operations.
The log-dynamic brain: how skewed distributions affect network operations.
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DOI:
10.1038/nrn3687
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发表时间:
2014-04
影响因子:
34.7
通讯作者:
Mizuseki, Kenji
中科院分区:
文献类型:
--
作者:
Buzsaki, Gyoergy;Mizuseki, Kenji
We often assume that the variables of functional and structural brain parameters — such as synaptic weights, the firing rates of individual neurons, the synchronous discharge of neural populations, the number of synaptic contacts between neurons and the size of dendritic boutons — have a bell-shaped distribution. However, at many physiological and anatomical levels in the brain, the distribution of numerous parameters is in fact strongly skewed with a heavy tail, suggesting that skewed (typically lognormal) distributions are fundamental to structural and functional brain organization. This insight not only has implications for how we should collect and analyse data, it may also help us to understand how the different levels of skewed distributions — from synapses to cognition — are related to each other.
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DOI:
10.1038/nrn3241
发表时间:
2012-05-18
期刊:
Nature reviews. Neuroscience
影响因子:
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作者:
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通讯作者:
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影响因子:
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通讯作者:
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通讯作者:
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