Evaluation of carotid atherosclerotic plaque surface characteristics utilizing simultaneous noncontrast angiography and intraplaque hemorrhage (SNAP) technique.

Evaluation of carotid atherosclerotic plaque surface characteristics utilizing simultaneous noncontrast angiography and intraplaque hemorrhage (SNAP) technique.
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利用同步非造影血管造影和斑块内出血 (SNAP) 技术评估颈动脉粥样硬化斑块表面特征。

DOI:
10.1002/jmri.25815
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发表时间:
2018-03
期刊:
Journal of magnetic resonance imaging : JMRI
影响因子:
--
通讯作者:
Zhao X
Zhao X
中科院分区:
其他
文献类型:
--
作者:
Chen S;Zhao H;Li J;Zhou Z;Li R;Balu N;Yuan C;Chen H;Zhao X

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评价同步非造影剂血管造影和斑块内出血(SNAP)技术在识别颈动脉斑块表面特征方面与传统多重对比血管壁成像方案相比的可行性。入选30例有症状的颈动脉斑块患者,采用常规多重对比方案和SNAP序列进行颈动脉磁共振成像(MRI)(3.0T)。作为一种固有的多对比度序列,SNAP可以生成灰色血液参考(Ref)图像集、黑色血液校正的真实的(CR)图像集和亮血MR血管造影(MRA)图像集。通过组合Ref和MRA图像来实现明亮的血液SNAP Ref 2图像,以便于斑块表面特征评价。评估是否存在钙化(CA)、腔内钙化(JCA)和溃疡。SNAP和多重对比血管壁协议之间的协议,确定CA,JCA和溃疡进行了分析,使用科恩的kappa分析。还评估了SNAP成像在识别斑块表面特征方面的阅片者间和阅片者内再现性。SNAP和传统多重对比方案在识别CA(κ = 0.74,95%置信区间[CI]:0.54-0.93)、JCA(κ = 0.81,95% CI:0.66-0.97)和溃疡(κ = 0.82,95% CI:0.65-0.99)方面的一致性良好至极好。此外,SNAP成像在CA、JCA和溃疡的识别中发现了极好的阅片者内和阅片者间重现性。SNAP成像显示出与多对比成像的良好一致性,并且在识别JCA和溃疡方面具有较高的重现性,这表明SNAP成像可能是识别颈动脉斑块表面特征的一种时间效率高的替代工具。
To evaluate the feasibility of the Simultaneous Noncontrast Angiography and intraPlaque hemorrhage (SNAP) technique in identification of carotid plaque surface characteristics compared with the conventional multicontrast vessel wall imaging protocol. Thirty symptomatic patients with carotid plaque were recruited and underwent carotid artery magnetic resonance imaging (MRI) (3.0T) using a conventional multicontrast protocol and SNAP sequence. As an intrinsic multicontrast sequence, SNAP could generate a gray blood reference (Ref) image set, a black blood corrected real (CR) image set, and a bright blood MR angiography (MRA) image set. A bright blood SNAP Ref2 image was implemented by combining Ref and MRA images for facilitating plaque surface characteristics evaluation. The presence/absence of calcification (CA), juxtaluminal calcification (JCA), and ulceration was assessed. The agreement between SNAP and multicontrast vessel wall protocol in identifying CA, JCA, and ulceration was analyzed using Cohen’s kappa analysis. The interreader and intrareader reproducibility of SNAP imaging in identifying plaque surface characteristics was also assessed. Good to excellent agreement was found between SNAP and conventional multicontrast protocol in identifying CA (κ = 0.74, 95% confidence interval [CI]: 0.54–0.93), JCA (κ = 0.81, 95% CI: 0.66–0.97), and ulceration (κ = 0.82, 95% CI: 0.65–0.99). In addition, excellent intrareader and interreader reproducibility was found for SNAP imaging in identification of CA, JCA, and ulceration. SNAP imaging showed excellent agreement with multicontrast imaging and high reproducibility in identification of both JCA and ulceration, suggesting that SNAP imaging may be a time-efficient, alternative tool in identification of plaque surface characteristics in carotid arteries.
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发表时间: 2009-09
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影响因子: 5.9
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DOI: 10.1016/j.jacc.2013.05.071
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