Overweight modifies the association between long-term ambient air pollution and prehypertension in Chinese adults: the 33 Communities Chinese Health Study.
Overweight modifies the association between long-term ambient air pollution and prehypertension in Chinese adults: the 33 Communities Chinese Health Study.
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超重改变了中国成年人长期环境空气污染与高血压前期之间的关系：33个社区中国健康研究
DOI：
10.1186/s12940-018-0401-2
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发表时间：
2018-06-28
期刊：
影响因子：
--
通讯作者：
Dong GH
中科院分区：
文献类型：
--
作者：
Yang BY;Qian ZM;Vaughn MG;Howard SW;Pemberton JP;Ma H;Chen DH;Hu LW;Zeng XW;Zhang C;Tian YP;Nian M;Xiao X;Dong GH
背景关于环境空气污染和超重对高血压前期的相互作用的研究很少。我们的目的是测试是否超重修改长期暴露于环境空气污染和高血压前期在中国adultes.MethodsA共16,188中国成年人，年龄在18-74岁，从33个社区在3个中国东北城市之间的关联进行了评估。计算了监测站空气动力学直径≤ 10 μm的颗粒物（PM10）、二氧化硫（SO2）、二氧化氮（NO2）和臭氧（O3）的三年平均水平。广义加性模型和2水平回归analysis.ResultsWe观察到显着的相互作用，空气污染物和超重的高血压前期和血压。PM10、SO2、NO2和O3与高血压前期的相关性在超重参与者中显著（空气污染物四分位距的患病率比（PRR）：1.14-1.20），但在正常体重参与者中不显著（PRR：0.98-1.04）。PM10、SO2和O3与收缩压（SBP）显著相关，超重成人（SBP/空气污染物IQR增加：1.82-4.53 mmHg）与正常体重成人（SBP增加：0.42-0.61 mmHg）的相关程度更高。对于舒张压（DBP），主要在超重参与者中观察到显著相关性（DBP增加：0.80-1.63 mmHg）。进一步的分层分析表明，所有这些相互作用更强的妇女，老年人，和参与者生活在收入水平较低或人口密度较高的地区。ConclusionsBeing超重可能会提高环境空气污染对高血压前期和血压在中国成年人的影响。
BackgroundResearch regarding the interaction of ambient air pollution and overweight on prehypertension is scarce. We aimed to test whether overweight modifies the association between long-term exposure to ambient air pollution and prehypertension in Chinese adults.MethodsA total of 16,188 Chinese adults, aged 18–74 years old, from 33 communities in 3 Northeastern Chinese cities were evaluated. Three-year average levels of particles with an aerodynamic diameter ≤ 10 μm (PM10), sulfur dioxides (SO2), nitrogen dioxides (NO2), and ozone (O3) were calculated at monitoring stations. Generalized additive models and 2-level regression analyses were applied.ResultsWe observed significant interactions between air pollutants and overweight on prehypertension and blood pressure. The associations of PM10, SO2, NO2, and O3with prehypertension were significant among overweight participants (Prevalence Rate Ratios (PRRs) per interquartile range (IQR) of air pollutants: 1.14–1.20), but not among normal weight participants (PRRs: 0.98–1.04). PM10, SO2, and O3were significantly associated with systolic blood pressure (SBP), and the magnitudes of these associations were higher among overweight adults (increases in SBP per IQR of air pollutants: 1.82–4.53 mmHg) than those among normal weight adults (increases in SBP: 0.42–0.61 mmHg). For diastolic blood pressure (DBP), significant associations were mainly observed in overweight participants (increases in DBP: 0.80–1.63 mmHg). Further stratified analyses showed that all these interactions were stronger in women, the older, and participants living in areas with lower income levels or higher population density.ConclusionsBeing overweight may enhance the effects of ambient air pollution on prehypertension and blood pressure in Chinese adults.
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影响因子：
10.4
作者：
Baumgartner J;Schauer JJ;Ezzati M;Lu L;Cheng C;Patz JA;Bautista LE
通讯作者：
Bautista LE
影响因子：
10.4
作者：
Babisch W;Wolf K;Petz M;Heinrich J;Cyrys J;Peters A
通讯作者：
Peters A
影响因子：
10.4
作者：
Baja ES;Schwartz JD;Wellenius GA;Coull BA;Zanobetti A;Vokonas PS;Suh HH
通讯作者：
Suh HH
DOI：
10.1097/ede.0000000000000422
发表时间：
2016-03
期刊：
Epidemiology (Cambridge, Mass.)
影响因子：
--
作者：
Kioumourtzoglou MA;Schwartz J;James P;Dominici F;Zanobetti A
通讯作者：
Zanobetti A
影响因子：
168.9
作者：
Lewington, S;Clarke, R;Collins, R
通讯作者：
Collins, R