Indoor air pollution and blood pressure in adult women living in rural China.
Indoor air pollution and blood pressure in adult women living in rural China.
复制标题
DOI：
10.1289/ehp.1003371
复制
发表时间：
2011-10
影响因子：
10.4
通讯作者：
Bautista LE
中科院分区：
文献类型：
--
作者：
Baumgartner J;Schauer JJ;Ezzati M;Lu L;Cheng C;Patz JA;Bautista LE
背景：世界上几乎一半的人口使用煤和生物质燃料作为家庭能源。有限的证据表明，暴露于室内生物质燃烧产生的空气污染物可能与血压升高有关。目的：我们的目的是评估中国农村妇女室内生物质燃烧空气污染暴露与血压之间的关系。研究方法：我们测量了280名年龄≥ 25岁、生活在云南使用生物质燃料的农村家庭的女性在冬季和夏季对空气动力学直径< 2.5 µm的细颗粒物（PM2.5）的24小时个人综合重力暴露以及收缩压（SBP）和舒张压（DBP）。我们研究了PM2.5暴露与SBP和DBP之间的关联，使用随机截距的混合效应模型来解释重复测量之间的相关性。结果：冬季个人平均24小时PM2.5暴露量范围为22至634 µg/m3，夏季为9至492 µg/m3。在所有女性中，PM2.5暴露增加1 log µg/m3与SBP升高2.2 mmHg [95%置信区间（CI），0.8至3.7; p = 0.003]和DBP升高0.5 mmHg（95% CI，-0.4至1.3; p = 0.31）相关;估计的影响因年龄组而异。在年龄> 50岁的女性中，PM2.5暴露增加1-log-µg/m3与SBP升高4.1 mmHg（95% CI，1.5至6.6; p = 0.002）和DBP升高1.8 mmHg（95% CI，0.4至3.2; p = 0.01）相关。在年轻女性中，PM2.5暴露与SBP呈正相关，但这种相关性没有统计学意义。结论：生物质燃烧产生的PM2.5暴露可能是血压升高和心血管事件的危险因素。我们的发现应该在纵向研究中得到证实。
Background: Almost half of the world’s population uses coal and biomass fuels for domestic energy. Limited evidence suggests that exposure to air pollutants from indoor biomass combustion may be associated with elevated blood pressure (BP). Objective: Our aim was to assess the relationship between air pollution exposure from indoor biomass combustion and BP in women in rural China. Methods: We measured 24-hr personal integrated gravimetric exposure to fine particles < 2.5 µm in aerodynamic diameter (PM2.5) and systolic BP (SBP) and diastolic BP (DBP) in the winter and summer among 280 women ≥ 25 years of age living in rural households using biomass fuels in Yunnan, China. We investigated the association between PM2.5 exposure and SBP and DBP using mixed-effects models with random intercepts to account for correlation among repeated measures. Results: Personal average 24-hr exposure to PM2.5 ranged from 22 to 634 µg/m3 in winter and from 9 to 492 µg/m3 in summer. A 1-log-µg/m3 increase in PM2.5 exposure was associated with 2.2 mm Hg higher SBP [95% confidence interval (CI), 0.8 to 3.7; p = 0.003] and 0.5 mm Hg higher DBP (95% CI, –0.4 to 1.3; p = 0.31) among all women; estimated effects varied by age group. Among women > 50 years of age, a 1-log-µg/m3 increase in PM2.5 exposure was associated with 4.1 mm Hg higher SBP (95% CI, 1.5 to 6.6; p = 0.002) and 1.8 mm Hg higher DBP (95% CI, 0.4 to 3.2; p = 0.01). PM2.5 exposure was positively associated with SBP among younger women, but the association was not statistically significant. Conclusion: PM2.5 exposure from biomass combustion may be a risk factor for elevated BP and hence for cardiovascular events. Our findings should be corroborated in longitudinal studies.
登录
查看更多内容
DOI：
10.1363/3006804
发表时间：
2004-06-01
期刊：
INTERNATIONAL FAMILY PLANNING PERSPECTIVES
影响因子：
--
作者：
Hardee, K;Xie, ZM;Gu, BC
通讯作者：
Gu, BC
DOI：
10.2471/blt.07.044529
发表时间：
2008-05-01
期刊：
Bulletin of the World Health Organization: International Journal of Public Health
影响因子：
--
作者：
Dherani, Mukesh;Pope, Daniel;Bruce, Nigel
通讯作者：
Bruce, Nigel
影响因子：
4.9
作者：
Brook, Robert D.;Bard, Robert L.;Williams, Ron
通讯作者：
Williams, Ron
影响因子：
8.3
作者：
Harrabi, I;Rondeau, V;Filleul, L
通讯作者：
Filleul, L
影响因子：
2.7
作者：
Bautista, LE;Vera, LM;Gamarra, G
通讯作者：
Gamarra, G