Obstructive sleep apnea among obese patients with type 2 diabetes.

Obstructive sleep apnea among obese patients with type 2 diabetes.
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DOI:
10.2337/dc08-1776
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发表时间:
2009-06
期刊:
影响因子:
16.2
通讯作者:
Sleep AHEAD Research Group
Sleep AHEAD Research Group
中科院分区:
医学1区
文献类型:
--
作者:
Foster GD;Sanders MH;Millman R;Zammit G;Borradaile KE;Newman AB;Wadden TA;Kelley D;Wing RR;Sunyer FX;Darcey V;Kuna ST;Sleep AHEAD Research Group

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评估肥胖合并2型糖尿病患者中阻塞性睡眠呼吸暂停(OSA)的存在和严重程度的危险因素。在306名参与者中进行了无人值守的多导睡眠图。超过86%的参与者患有OSA,呼吸暂停低通气指数(AHI)≥5次事件/h。平均AHI为20.5 ± 16.8起事件/h。共有30.5%的参与者患有中度OSA(15 ≤ AHI <30),22.6%患有重度OSA(AHI ≥30)。腰围(比值比1.1; 95%CI 1.0-1.1; P = 0.03)与OSA的存在显著相关。重度OSA最可能发生在BMI较高的个体中(比值比1.1; 95% CI 1.0-1.2; P = 0.03)。医生应该特别认识到2型糖尿病肥胖患者发生OSA的可能性,特别是腰围和BMI较高的患者。
To assess the risk factors for the presence and severity of obstructive sleep apnea (OSA) among obese patients with type 2 diabetes. Unattended polysomnography was performed in 306 participants. Over 86% of participants had OSA with an apnea-hypopnea index (AHI) ≥5 events/h. The mean AHI was 20.5 ± 16.8 events/h. A total of 30.5% of the participants had moderate OSA (15 ≤ AHI <30), and 22.6% had severe OSA (AHI ≥30). Waist circumference (odds ratio 1.1; 95% CI 1.0–1.1; P = 0.03) was significantly related to the presence of OSA. Severe OSA was most likely in individuals with a higher BMI (odds ratio 1.1; 95% CI 1.0–1.2; P = 0.03). Physicians should be particularly cognizant of the likelihood of OSA in obese patients with type 2 diabetes, especially among individuals with higher waist circumference and BMI.
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