Appropriateness of carotid plaque and intima-media thickness assessment in routine clinical practice.
Appropriateness of carotid plaque and intima-media thickness assessment in routine clinical practice.
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DOI：
10.1186/1476-7120-6-52
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发表时间：
2008-10-16
影响因子：
1.9
通讯作者：
Précoma DB
中科院分区：
文献类型：
--
作者：
Baroncini LA;de Oliveira A;Vidal EA;França GJ;Stahlke PS;Alessi A;Précoma DB
描述颈动脉研究的结果并评价其适当性，包括IMT测量、动脉粥样硬化斑块的存在及其与心血管危险因素的相关性。555例患者（220例男性; 67.06 ± 12.44岁）入组研究。120例（21.62%）患者存在颈动脉斑块：108例（19.45%）患者至少有一种危险因素，12例（2.1%）患者无危险因素。关于目前研究的适当性：65%是适当的，22%是不确定的，13%是不适当的。男性（0.0280; 95% CI，00.82 - 0.478; p = 0.0057）和高血压患者（0.391; 95% CI，0.0190 - 0.0592; p = 0.001）的IMT中位数较高。平均IMT随年龄的增加而线性增加（0.0059; 95% CI; 0.0050 - 0.0067）。颈动脉斑块在CAD（p = 0.0002）、糖尿病（p = 0.024）和高血压（p = 0.036）患者中更常见。对颈动脉的评估表明，冠心病、糖尿病和高血压患者的斑块发生率增加。老年患者、高血压患者和男性IMT增加。45%的患者是基于不确定和不适当的原因进行研究的。
To describe the findings and evaluate appropriateness of a carotid artery study including the measurement of IMT, the presence of atherosclerotic plaque, and their correlation with cardiovascular risk factors. 555 patients (220 men; 67.06 ± 12.44 years) were included in the study. 120 patients (21.62%) presented carotid plaque: 108 (19.45%) in patients with at least one risk factor and 12 (2.1%) in patients without risk factors. With respect to appropriateness of the present studies: 65% were appropriate, 22% were uncertain and 13% were inappropriate. The IMT medians were higher in males (0.0280; 95% CI, 00.82 to 0.478; p = 0.0057) and in hypertensive patients (0.391; 95% CI, 0.0190 to 0.0592; p = 0,001). There was a linear increase in mean IMT for each year increased in age (0.0059; 95% CI; 0.0050 to 0.0067). Carotid plaque was more frequent in patients with CAD (p = 0.0002), diabetes (p = 0.024) and hypertension (p = 0.036). Assessment of carotid arteries identified increased incidence of plaque in patients with CAD, diabetes and hypertension. IMT was increased in older patients, hypertensive patients and males. Forty-five percent of the patients were studied based on uncertain and inappropriate reasons.
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影响因子：
13.6
作者：
Benedetto, FA;Mallamaci, F;Zoccali, C
通讯作者：
Zoccali, C
影响因子：
5.8
作者：
Shishehbor, Mehdi H;Bhatt, Deepak L
通讯作者：
Bhatt, Deepak L
影响因子：
2.9
作者：
Touboul, PJ;Hennerici, G;Zannad, F
通讯作者：
Zannad, F
DOI：
10.1016/j.echo.2007.11.011
发表时间：
2008-02-01
影响因子：
6.5
作者：
Stein, James H.;Korcarz, Claudia E.;Post, Wendy S.
通讯作者：
Post, Wendy S.
影响因子：
37.8
作者：
Lombardo, A;Biasucci, LM;Maseri, A
通讯作者：
Maseri, A